| Name | L-Asparaginase |
|---|---|
| Synonyms |
IUB: 3.5.4.4
Benzisothiazolone L-ASPARAGINASE T56 BSMVJ ASPARAGINASE benzo[d]isothiazol-3-one 1,2-Benzisothiazol-3(2H)-one EC 3.5.1.1 T56 BSNJ DQ crasnitin L-ASPARAGINE AMIDOHYDROLASE 1,2-Benzothiazol-3(2H)-one elspar 1,2-Benzisothiazol-3-ol 1,2-Benzothiazol-3-ol Benzisothiazolone (BIT) colaspase |
| Description | L-Asparaginase (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 204.5±23.0 °C at 760 mmHg |
| Molecular Formula | C7H5NOS |
| Molecular Weight | 151.186 |
| Flash Point | 77.5±22.6 °C |
| Exact Mass | 151.009186 |
| LogP | 1.78 |
| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
| Index of Refraction | 1.745 |
| Storage condition | 2-8°C |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H361 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,Xn |
| Risk Phrases | 61-42/43-63 |
| Safety Phrases | 53-22-36/37/39-45-36/37 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | CI9000000 |
| Packaging Group | II |