Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

4-Sulfo-N-(4-aminobenzyl)-1,8-naphthalimide potassium

4-Sulfo-N-(4-aminobenzyl)-1,8-naphthalimide potassium is an inactive 1,8-Naphthalimide derivative. 4-Sulfo-N-(4-aminobenzyl)-1,8-naphthalimide potassium can be used as a negative control for the clathrin inhibitor 3-Sulfo-N-benzyl-1,8-naphthalimide, potassium salt[1].

  • CAS Number: 1419320-93-6
  • MF: C19H13KN2O5S
  • MW: 420.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LY 78335

1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1].

  • CAS Number: 39959-66-5
  • MF: C8H10Cl3N
  • MW: 226.53100
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-Campesterol-d6

(S)-Campesterol-d6 is deuterium labeled (S)-Campesterol.

  • CAS Number: 2260669-13-2
  • MF: C28H42D6O
  • MW: 406.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ISA-2011B

ISA-2011B is a PIP5Kα inhibitor with promising anticancer effects .

  • CAS Number: 1395347-24-6
  • MF: C22H18ClN3O4
  • MW: 423.849
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 714.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 386.1±32.9 °C

IsocoluMbin

Isocolumbin is a diterpenoid isolated from Jateorhiza palmate Miers (Colombo root)[1].

  • CAS Number: 471-54-5
  • MF: C20H22O6
  • MW: 358.385
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 565.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 296.0±30.1 °C

BOC-HIS(DNP)-OH

(S)-2-((tert-Butoxycarbonyl)amino)-3-(1-(2,4-dinitrophenyl)-1H-imidazol-4-yl)propanoic acid is a histidine derivative[1].

  • CAS Number: 25024-53-7
  • MF: C17H19N5O8
  • MW: 421.362
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 663.2±55.0 °C at 760 mmHg
  • Melting Point: 98ºC
  • Flash Point: 354.9±31.5 °C

1-Bromo-2,3-dichlorobenzene-d3

1-Bromo-2,3-dichlorobenzene-d3 is the deuterium labeled 1-Bromo-2,3-dichlorobenzene[1].

  • CAS Number: 1219805-59-0
  • MF: C6H3BrCl2
  • MW: 225.898
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 241.5±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 108.7±11.9 °C

RTC-30

RTC-30 is an optimized phenothiazine with anti-cancer potency. RTC-30 contains a hydroxylated linker (N) that confers increased oral bioavailability[1].

  • CAS Number: 1423077-95-5
  • MF: C24H23F3N2O4S
  • MW: 492.51
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Advantame

Advantame is a non-caloric artificial sweetener, analogue of aspartame, commonly used as a food additive[1].

  • CAS Number: 714229-20-6
  • MF: C24H32N2O8
  • MW: 476.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyaonoside B

β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate, as a saponin, has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex[1].

  • CAS Number: 51161-58-1
  • MF: C48H76O18
  • MW: 941.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sec61-IN-1

Sec61-IN-1 is a potent sec61 inhibitor (Patent WO2020176863A1, compound A317)[1].

  • CAS Number: 2484865-42-9
  • MF: C23H22N6OS
  • MW: 430.53
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ICG-OSu

ICG-OSu (ICG NHS ester), a near-infrared fluorescent agent, is amine-reactive and has been widely used to design in vivo imaging probes[1].

  • CAS Number: 1622335-40-3
  • MF: C49H53N3O7S
  • MW: 828.03
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Z-Cys-OH)2

(Z-Cys-OH)2 is a cysteine derivative[1].

  • CAS Number: 6968-11-2
  • MF: C22H24N2O8S2
  • MW: 508.565
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 766.1±60.0 °C at 760 mmHg
  • Melting Point: 118-122 °C (dec.)
  • Flash Point: 417.1±32.9 °C

Pareptide monohydrochloride

Pareptide monohydrochloride is a melanotropin-inhibiting factor (MIF) metabolically stable analogue.

  • CAS Number: 63236-23-7
  • MF: C14H27ClN4O3
  • MW: 334.842
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Rhodojaponin V

Rhodojaponin V is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity[1].

  • CAS Number: 37720-86-8
  • MF: C22H34O7
  • MW: 410.501
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 551.8±50.0 °C at 760 mmHg
  • Melting Point: 232 °C
  • Flash Point: 187.5±23.6 °C

Vat Blue 2

Vat Blue 2, a indigo (HY-N0335) derivative, is a dark blue 5,5'-dibromo-4,4'-dichloroindigo dye[1].

  • CAS Number: 29245-44-1
  • MF: C16H6Br2Cl2N2O2
  • MW: 488.94500
  • Catalog: Others
  • Density: 2.026g/cm3
  • Boiling Point: 556.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 290.2ºC

Dihydrofluorescein diacetate

Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.

  • CAS Number: 35340-49-9
  • MF: C24H18O7
  • MW: 418.39600
  • Catalog: Dye Reagents
  • Density: 1.353g/cm3
  • Boiling Point: 554.3ºC at 760 mmHg
  • Melting Point: 213-215ºC(lit.)
  • Flash Point: N/A

Gly-Gly-His

(S)-2-(2-(2-Aminoacetamido)acetamido)-3-(1H-imidazol-4-yl)propanoic acid is a histidine derivative[1].

  • CAS Number: 7451-76-5
  • MF: C10H15N5O4
  • MW: 269.25700
  • Catalog: Others
  • Density: 1.44
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-L-2-aminobutyric acid

Boc-L-2-aminobutanoic acid is an alanine derivative[1].

  • CAS Number: 34306-42-8
  • MF: C9H17NO4
  • MW: 203.236
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 334.5±25.0 °C at 760 mmHg
  • Melting Point: 70-74 °C
  • Flash Point: 156.1±23.2 °C

K-Casein (106-116),bovine

K-Casein (106-116),bovine is a peptide that inhibits platelet aggregation and fibrinogen binding, plays an important role in atherosclerosis[1].

  • CAS Number: 103951-35-5
  • MF: C55H96N16O16S
  • MW: 1269.51
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 4029-69-0
  • MF: C28H38O7
  • MW: 486.59700
  • Catalog: Cancer
  • Density: 1.24g/cm3
  • Boiling Point: 596.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 191.9ºC

Opicinumab

Opicinumab (BIIB033) is a monoclonal antibody against LINGO-1 and has potential application in acute optic neuritis and relapse multiple sclerosis[1][2].

  • CAS Number: 1422268-07-2
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-LOX-IN-1

5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].

  • CAS Number: 55040-82-9
  • MF: C20H18N2O2S
  • MW: 350.43
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ODN MT 01

ODN MT 01 is a synthetic oligodeoxynucleotide. ODN MT 01 can be used for experiment research[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pentanamide,N-(aminocarbonyl)-2-ethyl-3-methyl-

Capuride is an orally active sedative agent. Capuride has anticonvulsant activity[1].

  • CAS Number: 5579-13-5
  • MF: C9H18N2O2
  • MW: 186.25100
  • Catalog: Neurological Disease
  • Density: 1.009g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515

10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a fluorescent dye for Cu2+ ion[1].

  • CAS Number: 886212-87-9
  • MF: C27H32BF2N3O4
  • MW: 511.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

USP22-IN-1

USP22-IN-1 (compound S02) is a potent USP22 inhibitor. USP22-IN-1 decreases the expression of FOXP3, USP22 protein and Foxp3 mRNA levels. USP22-IN-1 enhanceds anti -tumor immunity[1].

  • CAS Number: 309735-96-4
  • MF: C22H18N4
  • MW: 338.41
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Methoxyphenylacetic acid

3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot[1].

  • CAS Number: 1798-09-0
  • MF: C9H10O3
  • MW: 166.174
  • Catalog: Infection
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 305.5±17.0 °C at 760 mmHg
  • Melting Point: 65-69 °C(lit.)
  • Flash Point: 124.1±14.4 °C

LEUCOPELARGONIDIN

Leucopelargonidin (compound IV) can be isolated from Connarus monocarpus[1].

  • CAS Number: 520-17-2
  • MF: C15H14O6
  • MW: 290.26800
  • Catalog: Others
  • Density: 1.605g/cm3
  • Boiling Point: 595.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 313.8ºC

ß-pBrPh-Glc

β-pBrPh-Glc is a small-molecule ice recrystallization inhibitor. β-pBrPh-Glc can control the rate and extent of intracellular ice recrystallization in the nuclei over a broad range of subzero temperatures. β-pBrPh-Glc is an important tool to improve the recovery and function of cryopreserved cells and tissues[1].

  • CAS Number: 30572-42-0
  • MF: C12H15BrO6
  • MW: 335.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A