5579-13-5
5579-13-5 structure
- Name: Pentanamide,N-(aminocarbonyl)-2-ethyl-3-methyl-
- Chemical Name: N-carbamoyl-2-ethyl-3-methylpentanamide
- CAS Number: 5579-13-5
- Molecular Formula: C9H18N2O2
- Molecular Weight: 186.25100
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-07-19 07:37:47
- Modify Date: 2025-08-26 12:32:20
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Capuride is an orally active sedative agent. Capuride has anticonvulsant activity[1].
| Name | N-carbamoyl-2-ethyl-3-methylpentanamide |
|---|---|
| Synonyms |
CAPURIDE
McN-X-94 2-Ethyl-3-methylpentanoyl-harnstoff 1-(2-ethyl-3-methyl-pentanoyl)-urea (2-ethyl-3-methyl-valeryl)-urea Pacinox (Ethyl-sec-butylacetyl)urea (2-Aethyl-3-methyl-valeryl)-harnstoff mcn-x 9 Capurid sec.Butylethylacetylharnstoff |
| Description | Capuride is an orally active sedative agent. Capuride has anticonvulsant activity[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Capuride (VPA, 38-107 mg/kg p.o.) shows anticonvulsant activity in MES and scMet induced seizures rats[2]. Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg[2]. Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in 6 Hz Psychomotor seizure mice[2]. Animal Model: Electrically (MES) and chemically (scMet) induced seizures in rats[2] Dosage: 38-107 mg/kg Administration: Oral administration (p.o.) Result: ED50s: 54 mg/kg (MES model), 77 mg/kg (scMet model). |
| Density | 1.009g/cm3 |
|---|---|
| Molecular Formula | C9H18N2O2 |
| Molecular Weight | 186.25100 |
| Exact Mass | 186.13700 |
| PSA | 72.19000 |
| LogP | 2.34480 |
| Index of Refraction | 1.463 |
|
~%
5579-13-5 |
| Literature: Volwiler; Tabern Journal of the American Chemical Society, 1936 , vol. 58, p. 1352 Chem. Zentralbl., 1935 , vol. 106, # I p. 1271 Full Text View citing articles Show Details Abbott Labor. Patent: US1969828 , 1931 ; |
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5579-13-5 |
| Literature: Kaufmann, Dan; Bialer, Meir; Shimshoni, Jakob Avi; Devor, Marshall; Yagen, Boris Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7236 - 7248 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |