55040-82-9

55040-82-9 structure

Name: 5-LOX-IN-1
Chemical Name: Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-
CAS Number: 55040-82-9
Molecular Formula: C₂₀H₁₈N₂O₂S
Molecular Weight: 350.43
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-08-17 15:13:31
Modify Date: 2024-01-13 18:12:51
5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].

Name	Methanone, [2-(4-morpholinyl)-4-phenyl-5-thiazolyl]phenyl-

Description	5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: 2.3 μM (5-LOX)[1]
In Vitro	5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM[1].
References	[1]. Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50.