10-Undecen-1-ol, converted from ricinoleic acid, can be used as a comonomer for the introduction of functional groups[1][2].
RM-581, an aminosteroid derivative, has potent anticancer activity in different types of cancer, including high fatality pancreatic cancer[1].
2-NP-AOZ is a 2-nitrophenyl derivative of AOZ (HY-W012982, a tissue-bound metabolite of the Furazolidone). 2-NP-AOZ can be used to determination of the AOZ residues[1][2].
LCMV GP (61-80) is a peptide fragment derived from lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), corresponds to amino acids 61-80. LCMV GP (61-80) is a specific epitope which can induce CD4+ T-cell response[1][2][3].
25-O-Acetylcimigenol xyloside is a triterpene xyloside that can be isolated from Cimicifuga racemosa[1].
AA74-1 is a potent and selective inhibitor of APEH. AA74-1 significantly increases T cells proliferation by blocking the APEH activity[1].
Fmoc-Ser(Trt)-OH is a serine derivative[1].
2-(2-Aminopropanamido)-4-methylpentanoic acid is a leucine derivative[1].
Faradiol is a triterpenoid. Faradiol can be isolated from the aerial parts of Dittrichia viscose[1].
2-Aminopurine-O-Ph-NHCO-C3-NHS ester (BG-GLA-NHS) is an amine-reactive building block. 2-Aminopurine-O-Ph-NHCO-C3-NHS ester can be used to modify viral capsids surface, and the synthesis of SNAP-tag substrates[1].
Cryptomeridiol can be isolated from Phaulopsis imbricata. Cryptomeridiol has melanogenesis inhibitory activity in the α-MSH-stimulated B16 melanoma cells[1].
(1R,3S)-Compound E is the inactive isomer of Compound E (HY-14176), and can be used as an experimental control. Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
Ethyl 2-oxo-4-phenylbutanoate-d5 is the deuterium labeled Ethyl 2-oxo-4-phenylbutanoate[1].
(S)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic acid is a Glycine (HY-Y0966) derivative[1].
Aβ1-42 aggregation inhibitor 1 inhibits AChE (acetylcholinesterase) and BuChE (butyrylcholinesterase) with the IC 50 value of 2.64 μM and 1.29 μM, respectively. Aβ1-42 aggregation inhibitor 1 inhibits self-mediated Aβ1-42 aggregation by 51.29% at a concentration of 25 μM. Aβ1-42 aggregation inhibitor 1 has the potential for the research of anti-Alzheimer's disease [1] .
1-Dehydroxy-23-deoxojessic acid (compound 10) is a cycloartane-type triterpene. 1-Dehydroxy-23-deoxojessic acid exhibits cytotoxicity against murine colon 26-L5 carcinoma cells, with an EC50 of 62.38 μM[1].
6-(3,4,5-Trimethoxybenzamido)hexanoic acid is an antiarrythmic agent[1].
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative[1].
Zhebeirine (Puqiedinone) is a steroidal alkaloid, is isolated from the bulbs of Fritillaria puqiensis. Zhebeirine exhibits antitussive and expectorant properties[1][2].
H-Thr-Met-OH is a biologically active peptide.
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate is a highly functionalized ingol diterpene that can be isolated from Euphorbia officinarum latex[1].
Stigmasta-3,5-dien-7-one is a steroid compound derived from Harrisonia abyssinica[1].
Quercetin 3-O-rutinoside-7-O-glucoside (compound 8) is an antioxidant agent that canbe found in Hemerocallis fulva. Quercetin 3-O-rutinoside-7-O-glucoside shows strong lipid peroxidation inhibitory activities[1].
Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii).
X-Gluc sodium is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system)[1].
Aclacinomycin A hydrochloride (Aclarubicin hydrochloride), a fluorescent molecule, is an effective anthracycline chemotherapeutic agent for hematologic cancers and solid tumors. Accumulates efficiently in the mitochondria of living human cells and leads to mitochondrial dysfunction[1].
PEN (human) is an endogenous peptide GPR83 agonist.
Loganic acid 6′-O-β-D-glucoside, a iridoidal glucoside, is isolated from the whole plant of Gentiana rhodantha (Gentianaceae). Loganic acid 6′-O-β-D-glucoside inhibits LPS-induced NO and TNF-α production in macrophage RAW264.7 cells[1].
Anthraquinone is used as a precursor for dye formation.
Glutaminase-IN-1, a CB839 derivative, is an allosteric inhibitor of 1,3,4-selenadiazole-containing kidney-type glutaminase (KGA), with an IC50 of 1 nM. Glutaminase-IN-1 shows improved cellular uptake and antitumor activity.