Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

FBBBE

FBBBE is used to detect the production of H2O2 by cells. FBBBE can be triggered by intracellular H2O2 and converted to fluorescein, resulting in an increase in intracellular fluorescence (Ex=4480 nm, Em=512 nm)[1].

  • CAS Number: 1522117-83-4
  • MF: C46H46B2O9
  • MW: 584.229
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 595.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 313.8±32.9 °C

Z-D-2-Nal-OH

Z-D-2-Nal-OH is an alanine derivative[1].

  • CAS Number: 143218-10-4
  • MF: C21H19NO4
  • MW: 349.38000
  • Catalog: Others
  • Density: 1.275g/cm3
  • Boiling Point: 591.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 311.5ºC

shoreic acid

Shoreic acid (compound 8a) is a dammarane skeleton compound isolated from Cabralea eichleriana DC[1].

  • CAS Number: 21671-00-1
  • MF: C30H50O4
  • MW: 474.72
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 568.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 174.3±22.2 °C

Hydroxy-gamma-sanshool

Hydroxy-γ-sanshool is an alkylamide exists in Zanthoxylum bungeanum oil and Zanthoxylum schinifolium oil[1].

  • CAS Number: 78886-66-5
  • MF: C18H27NO2
  • MW: 289.41200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

tetramethylbenzene

1,2,3,4-Tetramethylbenzene consists of a benzene ring with four methyl groups (-CH3) as a substituent. 1,2,3,4-Tetramethylbenzene is a specialty product for biochemistry research[1].

  • CAS Number: 488-23-3
  • MF: C10H14
  • MW: 134.218
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 204.0±35.0 °C at 760 mmHg
  • Melting Point: 76-80 °C(lit.)
  • Flash Point: 68.3±0.0 °C

Z-Gly-Pro-AMC

Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-amido-4-methylcoumarin (HY-D0027). (λex=380 nm, λem=465 nm)[1].

  • CAS Number: 68542-93-8
  • MF: C25H25N3O6
  • MW: 463.48300
  • Catalog: Others
  • Density: 1.358g/cm3
  • Boiling Point: 770.8ºC at 760 mmHg
  • Melting Point: 96-102ºC(lit.)
  • Flash Point: 420ºC

Sodium Gluconate

Sodium gluconate is a corrosion and scale inhibitor of ordinary steel in simulated cooling water.

  • CAS Number: 527-07-1
  • MF: C6H11NaO7
  • MW: 218.137
  • Catalog: Others
  • Density: 1.763g/cm3
  • Boiling Point: 673.6ºC at 760 mmHg
  • Melting Point: 206 °C (dec.)(lit.)
  • Flash Point: 375.2ºC

O-((Perfluorophenyl)methyl)hydroxylamine-d2 hydrochloride

O-((Perfluorophenyl)methyl)hydroxylamine-d2 (hydrochloride) is the deuterium labeled O-((Perfluorophenyl)methyl)hydroxylamine hydrochloride[1].

  • CAS Number: 358730-85-5
  • MF: C7H3ClD2F5NO
  • MW: 251.57800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Anemarrhenasaponin Ia

Anemarrhenasaponin Ia, isolated from Anemarrhenae rhizome, inhibits N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation. Anemarrhenasaponin Ia is an useful anti-inflammation reagent[1].

  • CAS Number: 221317-02-8
  • MF: C48H68O14
  • MW: 772.96
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

digoxigenin-bis(digitoxoside)

Digoxigenin bisdigitoxoside is an anticancer drug. Digoxigenin bisdigitoxoside is cytotoxic[1].

  • CAS Number: 5297-05-2
  • MF: C35H54O11
  • MW: 650.79700
  • Catalog: Cancer
  • Density: 1.34g/cm3
  • Boiling Point: 826ºC at 760mmHg
  • Melting Point: 260-262ºC
  • Flash Point: 256.9ºC

2'-OMe-Ac-C Phosphoramidite

2'-OMe-Ac-C Phosphoramidite is a modified phosphoramidite and can be used for the oligonucleotide synthesis.

  • CAS Number: 199593-09-4
  • MF: C42H52N5O9P
  • MW: 801.86400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetra-n-propyl-ammonium-d28 bromide

Tetra-n-propyl-ammonium-d28 (bromide) is the deuterium labeled Tetra-n-propyl-ammonium bromide[1].

  • CAS Number: 284474-84-6
  • MF: C12BrD28N
  • MW: 294.43400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 270ºC (dec.)(lit.)
  • Flash Point: N/A

2'-Fluoro-2'-deoxy Uridine CED Phosphoramidite

DMT-2′Fluoro-dU Phosphoramidite could be used for nucleoside modification.

  • CAS Number: 146954-75-8
  • MF: C39H46FN4O8P
  • MW: 748.777
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NSC668394

NSC668394 (NSC 668394) is a small molecule inhibitor of ezrin, directly bind to ezrin with Kd of 12.59 uM; inhibits T567 phosphorylation and actin binding of endogenous ezrin at 10 μM without altering cellular ezrin levels, inhibits PKC-Ι phosphorylation of recombinant ezrin with IC50 of 8.1 uM; inhibits ezrin-mediated invasion of K7M2 OS cells, inhibits cell motility during zebrafish and Xenopus embryonic development; also inhibits ezrin-dependent in vivo OS metastatic growth in mouse lung.

  • CAS Number: 382605-72-3
  • MF: C17H12Br2N2O3
  • MW: 452.097
  • Catalog: Cancer
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 575.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 301.6±30.1 °C

Ingol 7,8,12-triacetate 3-phenylacetate

Ingol 7,8,12-triacetate 3-phenylacetate (compound 1) is a highly functionalized ingol diterpene isolated from spurge rum latex. Ingol 7,8,12-triacetate 3-phenylacetate has no significant effect on the cell cycle.

  • CAS Number: 944799-46-6
  • MF: C33H40O10
  • MW: 596.66
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ICG-alkyne

ICG-alkyne is a click chemistry reagent containing an azide group[1].

  • CAS Number: 1622335-41-4
  • MF: C48H53N3O4S
  • MW: 768.02
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sucralfate

Sucralfate is a cytoprotective agent which has been employed for prevention and treatment of several gastrointestinal diseases.

  • CAS Number: 54182-58-0
  • MF: C12H14Al16O75S8
  • MW: 2046.42
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Nitrosodibutylamine

N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water[1].

  • CAS Number: 924-16-3
  • MF: C8H18N2O
  • MW: 158.24100
  • Catalog: Others
  • Density: 0.91 g/cm3
  • Boiling Point: 250.6ºC at 760 mmHg
  • Melting Point: <25℃
  • Flash Point: 105.3ºC

Desmedipham

Desmedipham is a selective systemic phenyl-carbamate herbicide. Desmedipham acts by disrupting CO2 fixation and the production of intermediary energy components-ATP and NADPH2 and inhibition of Hill reaction[1].

  • CAS Number: 13684-56-5
  • MF: C16H16N2O4
  • MW: 300.309
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 495.4±55.0 °C at 760 mmHg
  • Melting Point: 120 °C
  • Flash Point: 253.4±31.5 °C

Febuxostat amide impurity

Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1]

  • CAS Number: 1239233-86-3
  • MF: C16H18N2O4S
  • MW: 334.39000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetrapeptide-21

Tetrapeptide-21 is a bioactive peptide with anti-wrinkle and and reducing skin hyperpigmentation effect, and has been reported used as a cosmetic ingredient[1].

  • CAS Number: 960608-17-7
  • MF: C15H27N5O7
  • MW: 389.40400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kanshone C

Kanshone C is a sesquiterpenoid of Nardostachys chinensis roots[1].

  • CAS Number: 117634-64-7
  • MF: C15H20O3
  • MW: 248.31700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Allocholic acid

Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis. Allocholic acid is also a potent and specific stimulant of the adult olfactory system[1][2][3].

  • CAS Number: 2464-18-8
  • MF: C24H40O5
  • MW: 408.57100
  • Catalog: Others
  • Density: 1.184g/cm3
  • Boiling Point: 583.9ºC at 760 mmHg
  • Melting Point: 250-251ºC
  • Flash Point: 321ºC

Nα-Carbobenzoxy-D-histidine

Z-D-His-OH is a histidine derivative[1].

  • CAS Number: 67424-93-5
  • MF: C14H15N3O4
  • MW: 289.287
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 616.7±55.0 °C at 760 mmHg
  • Melting Point: 161-163ºC
  • Flash Point: 326.8±31.5 °C

Raloxifene Bismethyl Ether

Raloxifene Bismethyl Ether is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent[1].

  • CAS Number: 84541-38-8
  • MF: C30H31NO4S
  • MW: 501.63600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 75-85ºC
  • Flash Point: N/A

3-(4-Pyridinyl)alanine

H-4-Pal-OH is an alanine derivative[1].

  • CAS Number: 37535-49-2
  • MF: C8H10N2O2
  • MW: 166.177
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 346.4±32.0 °C at 760 mmHg
  • Melting Point: 260-262ºC
  • Flash Point: 163.3±25.1 °C

Jervinone

Jervinone is a metabolite of the Veratrum alkaloid, which can be isolated from the mold Cunninghamella echinulata[1].

  • CAS Number: 469-60-3
  • MF: C27H37NO3
  • MW: 423.58800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cynarin

1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid from Xanthii fructus, inhibits LPS-stimulated TNF-α production[1].

  • CAS Number: 1182-34-9
  • MF: C25H24O12
  • MW: 516.45
  • Catalog: Inflammation/Immunology
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 819.9±65.0 °C at 760 mmHg
  • Melting Point: 225-227ºC
  • Flash Point: 278.1±27.8 °C

H-Ala-Ala-Ala-Ala-Ala-OH

Penta-alanine (Penta-L-alanine) is a petide. Penta-alanine can be used for neurological disease research[1][2].

  • CAS Number: 10183-34-3
  • MF: C15H27N5O6
  • MW: 373.40500
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ACTH (2-24) (human, bovine, rat)

ACTH (2-24) (human, bovine, rat) is a peptide analogue of ACTH.

  • CAS Number: 67654-32-4
  • MF: C133H205N39O29S
  • MW: 2846.36
  • Catalog: Endocrinology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A