Raloxifene Bismethyl Ether

Modify Date: 2025-08-21 17:41:29

Raloxifene Bismethyl Ether Structure
Raloxifene Bismethyl Ether structure
Common Name Raloxifene Bismethyl Ether
CAS Number 84541-38-8 Molecular Weight 501.63600
Density N/A Boiling Point N/A
Molecular Formula C30H31NO4S Melting Point 75-85ºC
MSDS N/A Flash Point N/A

 Use of Raloxifene Bismethyl Ether


Raloxifene Bismethyl Ether is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent[1].

 Names

Name [6-methoxy-2-(4-methoxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone
Synonym More Synonyms

 Raloxifene Bismethyl Ether Biological Activity

Description Raloxifene Bismethyl Ether is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent[1].
Related Catalog
In Vitro Raloxifene Bismethyl Ether has no effect on tissue toughness in the ex vivo beam model[1].
References

[1]. Gallant MA, et al. Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties. Bone. 2014 Apr;61:191-200.

 Chemical & Physical Properties

Melting Point 75-85ºC
Molecular Formula C30H31NO4S
Molecular Weight 501.63600
Exact Mass 501.19700
PSA 76.24000
LogP 6.61910
InChIKey MSRYQTKAUSVEDP-UHFFFAOYSA-N
SMILES COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1

 Synthetic Route

 Synonyms

6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-piperidinylethoxy)benzoyl]benzo[b]thiophene
1-(2-{4-[6-methoxy-2-(4-methoxyphenyl)-benzo[b]thiophene-3-carbonyl]-phenoxy}-ethyl)-piperidine
Raloxifene Bismethyl Ether
(4-(2-(piperidin-1-yl)ethoxy)phenyl)(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)methanone
1-(2-{4-[6-Methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenoxy}-ethyl)-piperidin
[6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene][4-(2-(piperidin-1-yl)ethoxy)phenyl]methanone
6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene
[6-Methoxy-2-(4-methoxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone
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