Raloxifene 6-Monomethyl Ether

Modify Date: 2025-08-26 16:35:50

Raloxifene 6-Monomethyl Ether Structure
Raloxifene 6-Monomethyl Ether structure
Common Name Raloxifene 6-Monomethyl Ether
CAS Number 178451-13-3 Molecular Weight 487.61
Density N/A Boiling Point N/A
Molecular Formula C29H29NO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Raloxifene 6-Monomethyl Ether


Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1].

 Names

Name Raloxifene 6-Monomethyl Ether

 Raloxifene 6-Monomethyl Ether Biological Activity

Description Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1].
Related Catalog
In Vitro Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative with a methoxy group on C6. Raloxifene 6-Monomethyl Ether holds poor ICsub>50 value because of disruption to the hydrogen bond network and steric disfavor[1].
References

[1]. Chang YH, et al. Computational study of estrogen receptor-alpha antagonist with three-dimensional quantitative structure-activity relationship, support vector regression, and linear regression methods. Int J Med Chem. 2013;2013:743139.

 Chemical & Physical Properties

Molecular Formula C29H29NO4S
Molecular Weight 487.61
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