Raloxifene 6-Monomethyl Ether
Modify Date: 2025-08-26 16:35:50
Raloxifene 6-Monomethyl Ether structure
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Common Name | Raloxifene 6-Monomethyl Ether | ||
|---|---|---|---|---|
| CAS Number | 178451-13-3 | Molecular Weight | 487.61 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H29NO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Raloxifene 6-Monomethyl EtherRaloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1]. |
| Name | Raloxifene 6-Monomethyl Ether |
|---|
| Description | Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1]. |
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| Related Catalog | |
| In Vitro | Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative with a methoxy group on C6. Raloxifene 6-Monomethyl Ether holds poor ICsub>50 value because of disruption to the hydrogen bond network and steric disfavor[1]. |
| References |
| Molecular Formula | C29H29NO4S |
|---|---|
| Molecular Weight | 487.61 |
| InChIKey | KOFDGHCTXVZHIH-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(O)cc3)sc2c1 |