Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Bis[(2H5)phenyl] sulfide

Diphenylsulfane-d1 is the deuterium labeled Diphenylsulfane[1].

  • CAS Number: 180802-01-1
  • MF: C12D10S
  • MW: 196.334
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 296.0±9.0 °C at 760 mmHg
  • Melting Point: -40ºC(lit.)
  • Flash Point: 128.4±15.4 °C

(±)-Dihydroactinidiolide

(±)-Dihydroactinidiolide, an important aroma compound of black tea and tobacco, has been isolated from several plants. (±)-Dihydroactinidiolide can be formation from β-Carotene by the treatment of polyphenoloxidase, the lipoxygenase, and the xanthine oxidase[1][2].

  • CAS Number: 15356-74-8
  • MF: C11H16O2
  • MW: 180.243
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 296.1±9.0 °C at 760 mmHg
  • Melting Point: 42-43°
  • Flash Point: 120.2±16.1 °C

1,3-Dinitroglycerin-d5

1,3-Dinitroglycerin-d5 is the deuterium labeled 1,3-Dinitroglycerin[1].

  • CAS Number: 2733972-23-9
  • MF: C3HD5N2O7
  • MW: 187.12
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-bromo-1-[6-(dimethylamino)naphthalen-2-yl]ethanone

BADAN (6-Bromoacetyl-2-dimethylaminonaphthalene) is a polarity-sensitive fluorescent probe[1].

  • CAS Number: 210832-86-3
  • MF: C14H14BrNO
  • MW: 292.17100
  • Catalog: Others
  • Density: 1.416g/cm3
  • Boiling Point: 415.4ºC at 760mmHg
  • Melting Point: 117-120ºC
  • Flash Point: 205ºC

(S)-N-Boc-4-Bromophenylalanine

Boc-Phe(4-Br)-OH is a phenylalanine derivative[1].

  • CAS Number: 62129-39-9
  • MF: C14H18BrNO4
  • MW: 344.201
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 475.3±40.0 °C at 760 mmHg
  • Melting Point: 118ºC
  • Flash Point: 241.2±27.3 °C

Hexaconazole

Hexaconazole is a systemic fungicide used for the control of many fungi particularly Ascomycetes and Basidiomycetes. In vitro: Among the enzymatic antioxidants, superoxide dismutase and peroxidase are significantly up-regulated by hexaconazole. [1] Hexaconazole and its enantiomers cause the down-regulation of tryptophan levels and the up-regulation of kynurenine (KYN) levels, suggesting a role for hexaconazole in the activation of the KYN pathway and providing information for the mechanism of its toxicity.[2]

  • CAS Number: 79983-71-4
  • MF: C14H17Cl2N3O
  • MW: 314.210
  • Catalog: Fungal
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 490.3±55.0 °C at 760 mmHg
  • Melting Point: 111ºC
  • Flash Point: 250.3±31.5 °C

Cholesteryl caprylate

Cholesterol n-Octanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 1182-42-9
  • MF: C35H60O2
  • MW: 512.85000
  • Catalog: Others
  • Density: 0.97 g/cm3
  • Boiling Point: 565ºC at 760 mmHg
  • Melting Point: 110 °C(lit.)
  • Flash Point: N/A

Iodobenzene-d5

Iodobenzene-d5 is the deuterium labeled 1-Iodobenzene[1].

  • CAS Number: 7379-67-1
  • MF: C6D5I
  • MW: 209.03900
  • Catalog: Others
  • Density: 1.868 g/mL at 25ºC
  • Boiling Point: 188ºC(lit.)
  • Melting Point: -29ºC(lit.)
  • Flash Point: 74ºC

BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE

EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P2 phosphatase and Ins(1,4,5)P3 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity[1][2].

  • CAS Number: 20231-01-0
  • MF: C12H22N4S4
  • MW: 350.59000
  • Catalog: Phosphatase
  • Density: 1.339g/cm3
  • Boiling Point: 450.5ºC at 760 mmHg
  • Melting Point: 142ºC
  • Flash Point: 226.3ºC

BODIPY FL L-Cystine

BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm)[1][2].

  • CAS Number: 1180490-57-6
  • MF: C34H38B2F4N6O6S2
  • MW: 788.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Novaluron

Novaluron is a chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators.

  • CAS Number: 116714-46-6
  • MF: C17H9ClF8N2O4
  • MW: 492.70500
  • Catalog: Others
  • Density: 1.601 g/cm3
  • Boiling Point: N/A
  • Melting Point: 177.5ºC
  • Flash Point: N/A

(cis-1,4-Dihydroxycyclohexyl)acetic acid

Rengynic acid can be isolated from the seeds of Forsythia suspensa. Rengynic acid has potent antiviral effect on RSV[1].

  • CAS Number: 517883-38-4
  • MF: C8H14O4
  • MW: 174.19
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 385.9±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.4±20.2 °C

Dapiprazole Hydrochloride

Dapiprazole hydrochloride is a potent α-adrenergic blocking drug, which is used to reverse mydriasis after eye examination.(1) It inhibits amphetamine toxicity and alcohol and morphine withdrawal syndromes, produces sedation, blocks conditioned avoidance reflexes and reduces the response to noxious stimuli.(2) The orally administrated daily dose varied from 30 to 90 mg.

  • CAS Number: 72822-13-0
  • MF: C19H28ClN5
  • MW: 361.91
  • Catalog: Adrenergic Receptor
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 538.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 279.7±32.9 °C

Z-FA-FMK

(S,S)-Z-FA-FMK is a cell-permeable, irreversible cathepsin B inhibitor. (S,S)-Z-FA-FMK blocks LPS-induced production of IL-1α and IL-1β. (S,S)-Z-FA-FMK can be used as a negative control for caspase-1 and caspase-2 inhibitors because it lacks an aspartic acid residue at the P1 position[1][2].

  • CAS Number: 105637-38-5
  • MF: C21H23FN2O4
  • MW: 386.41700
  • Catalog: Cathepsin
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mavoglurant racemate

Mavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist.

  • CAS Number: 1636881-61-2
  • MF: C19H23NO3
  • MW: 313.391
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 476.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 241.8±28.7 °C

(Aminomethyl)phosphonic acid-d2

(Aminomethyl)phosphonic acid-d2 is the deuterium labeled (Aminomethyl)phosphonic acid[1].

  • CAS Number: 30926-24-0
  • MF: CH4D2NO3P
  • MW: 113.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Fluoro-2-nitrobenzene-13C6

1-Fluoro-2-nitrobenzene-13C6 is the 13C-labeled 1-Fluoro-2-nitrobenzene[1].

  • CAS Number: 2230123-14-3
  • MF: 13C6H4FNO2
  • MW: 147.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CEP dipeptide 1

CEP dipeptide 1 is a CEP dipeptide with potent angiogenic activity; mediators of age-related macular degeneration (AMD).

  • CAS Number: 816432-15-2
  • MF: C18H27N3O6
  • MW: 381.42300
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Asp(OtBu)-OH-13C4,15N

Fmoc-Asp(OtBu)-OH-13C4,15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].

  • CAS Number: 1160760-08-6
  • MF: C1913C4H2515NO6
  • MW: 416.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3β-Hydroxytaraxast-20-en-16-one

3β-Hydroxytaraxast-20-en-16-one is a natural product isolated from eucalyptol/alcohol extract[1].

  • CAS Number: 42482-69-9
  • MF: C30H48O2
  • MW: 440.70092
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Displurigen

Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM)[1].

  • CAS Number: 96156-26-2
  • MF: C15H10O4S
  • MW: 286.30300
  • Catalog: HSP
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Esomeprazole sodium

Esomeprazole sodium is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.IC50 value:Target: proton pumpEsomeprazole sodium (Nexium) is the S-isomer of omeprazole and acts as a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis. Esomeprazole 0.4 and 0.8 mg/mL as the sodium salt in the infusion solutions tested is chemically and physically stable for at least 2 days at room temperature and 5 days under refrigeration.

  • CAS Number: 161796-78-7
  • MF: C17H18N3NaO3S
  • MW: 367.398
  • Catalog: Proton Pump
  • Density: N/A
  • Boiling Point: 600ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 316.7ºC

10-Hydroxy majoroside

10-Hydroxy majoroside is a methanol extract isolated from plantago asiatica[1].

  • CAS Number: 259753-12-3
  • MF: C17H24O11
  • MW: 404.366
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydrocortisone Valerate

Hydrocortisone 17-valerate (Cortisol 17-valerate) is a thiazolidine compound[1].

  • CAS Number: 57524-89-7
  • MF: C26H38O6
  • MW: 446.57600
  • Catalog: Others
  • Density: 1.21g/cm3
  • Boiling Point: 595.1ºC at 760mmHg
  • Melting Point: 217-220 °C
  • Flash Point: 195ºC

Human enteropeptidase-IN-3

Human enteropeptidase-IN-3 is an enteropeptidase inhibitor. Human enteropeptidase-IN-3 exhibits enteropeptidase activity and long duration of inhibitory state. Human enteropeptidase-IN-3 can be used for intetinal digestive related diseases research[1].

  • CAS Number: 1958037-36-9
  • MF: C22H22N4O8
  • MW: 470.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glycosolone

Glycosoloneis a alkaloidthat can be found in Glycosmis pentaphylla[1].

  • CAS Number: 67879-81-6
  • MF: C16H19NO3
  • MW: 273.33
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 410.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.9±28.7 °C

1-(2H3)Methyl-2-azepanone

1-Methylazepan-2-one-d3 is the deuterium labeled 1-Methylazepan-2-one[1].

  • CAS Number: 203645-60-7
  • MF: C7H10D3NO
  • MW: 130.203
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 247.8±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 103.3±0.0 °C

5-Fluoro-4’-C-methyluridine

5-Fluoro-4’-C-methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

  • CAS Number: 660845-69-2
  • MF:
  • MW:
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

UNII:TL35μ1249

1,1'-Binaphthyl-2,2'-diamine is the inactive isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 4488-22-6
  • MF: C20H16N2
  • MW: 284.35
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 480.8±30.0 °C at 760 mmHg
  • Melting Point: 242-244ºC(lit.)
  • Flash Point: 293.9±24.0 °C

TRPC5-IN-2

TRPC5-IN-2 is a potent TRPC5 inhibitor (WO2019055966A2, Compound IO)[1].

  • CAS Number: 2304552-99-4
  • MF: C17H14ClF3N6O
  • MW: 410.78
  • Catalog: TRP Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A