Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Docusate sodium

Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.

  • CAS Number: 577-11-7
  • MF: C20H37NaO7S
  • MW: 444.558
  • Catalog: Others
  • Density: 1.1
  • Boiling Point: N/A
  • Melting Point: 173-179 °C(lit.)
  • Flash Point: 199ºC

5-hydroxy Thiabendazole

5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure[1].

  • CAS Number: 948-71-0
  • MF: C10H7N3OS
  • MW: 217.25
  • Catalog: Others
  • Density: 1.535g/cm3
  • Boiling Point: 525.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 271.7ºC

5α-Cholesta-7,24-dien-3β-ol-d6

5α-Cholesta-7,24-dien-3β-ol-d6 is deuterium labeled 5α-Cholesta-7,24-dien-3β-ol. 5α-Cholesta-7,24-dien-3β-ol, a sterol, can be found in hamster cauda epididymal mature spermatozoa[1].

  • CAS Number: 2260669-18-7
  • MF: C27H38D6O
  • MW: 390.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

z-arg-amc hcl

Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm)[1][2].

  • CAS Number: 70375-22-3
  • MF: C24H28ClN5O5
  • MW: 501.96300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 793ºC at 760 mmHg
  • Melting Point: 204-205ºC
  • Flash Point: 433.4ºC

(+)-EPI-QUERCITOL

(+)-epi-Quercitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 131435-06-8
  • MF: C6H12O5
  • MW: 164.15600
  • Catalog: Others
  • Density: 1.796g/cm3
  • Boiling Point: 293.641ºC at 760 mmHg
  • Melting Point: 192-197°C
  • Flash Point: 146.216ºC

Di-tert-butyl diisopropylphosphoramidoite

Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

  • CAS Number: 137348-86-8
  • MF: C14H32NO2P
  • MW: 277.39
  • Catalog: DNA/RNA Synthesis
  • Density: 0.879
  • Boiling Point: 252.2±9.0 °C at 760 mmHg
  • Melting Point: 85-90ºC 0.2 mm Hg(lit.)
  • Flash Point: 106.4±18.7 °C

Ethylenediaminetetraacetic acid (trisodium salt)

Ethylenediaminetetraacetic acid (EDTA) trisodium salt is used to bind metal ions in the practice of chelation therapy, for treating mercury and lead poisoning, used in a similar manner to remove excess iron from the body, for treating the complication of repeated blood transfusions, as would be applied to treat thalassaemia.

  • CAS Number: 150-38-9
  • MF: C10H13N2Na3O8
  • MW: 358.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 614.2ºC at 760 mmHg
  • Melting Point: 237 °C
  • Flash Point: 325.2ºC

5-Chloro-1,3-benzothiazol-2(3H)-one

5-Chloro-2-benzothiazolinone is an active compound. 5-Chloro-2-benzothiazolinone can be used for the research of various biochemical studies[1].

  • CAS Number: 20600-44-6
  • MF: C7H4ClNOS
  • MW: 185.631
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(1R, 3S, 4R)-ent-Entecavir

(1R,3S,4R)-ent-Entecavir ((1R,3S,4R)-ent-BMS200475; (1R,3S,4R)-ent-SQ34676) can be used to synthesize PROTAC targets to degrade deoxyribonucleic acid (DNA) polymerase[1].

  • CAS Number: 188399-46-4
  • MF: C12H15N5O3
  • MW: 277.279
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2H4)-1,3-Dioxolan-2-one

Ethylene carbonate-d4 is the deuterium labeled Ethylene carbonate[1].

  • CAS Number: 362049-63-6
  • MF: C3D4O3
  • MW: 92.087
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 248.2±0.0 °C at 760 mmHg
  • Melting Point: 34-37ºC
  • Flash Point: 160.0±0.0 °C

8-Methyl Chrysophanol

8-Methyl Chrysophanol is an anthraquinone isolated from the bark of Senna macranth[1].

  • CAS Number: 3300-25-2
  • MF: C16H12O4
  • MW: 268.26400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Karrikinolide

Karrikinolide is a phytoreactive compound derived from smoke with applications in horticulture, ecological restoration and agriculture. Karrikinolide has a regulatory effect on the concentrations of endogenous cytokinins and growth stimulatory activity in plants[1].

  • CAS Number: 857054-02-5
  • MF: C8H6O3
  • MW: 150.13100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 trifluoroacetate salt

NFF-3, the peptide, is a selective MMP substrate. NFF-3 selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity[1].

  • CAS Number: 158584-09-9
  • MF: C78H110N22O20
  • MW: 1675.84
  • Catalog: MMP
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Methyluridine-3′-13C

5-Methyluridine-3′-13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].

  • CAS Number: 478511-00-1
  • MF: C10H14N2O6
  • MW: 259.22100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DANSYL-X, SE

DANSYL-X, SE is an environmentally sensitive hydrophobic dye (Excitation 333 nM; Emission 518 nM). DANSYL-X, SE can increase fluorescence intensity in hydrophobic environment[1][2].

  • CAS Number: 217176-82-4
  • MF: C22H27N3O6S
  • MW: 461.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-(Imidazol-1-yl)phenol

4-(Imidazol-1-yl)phenol is a highly potent signal enhancer in a horseradish peroxidase (HRP)-luminol chemiluminescence (CL) immunoassay[1].

  • CAS Number: 10041-02-8
  • MF: C9H8N2O
  • MW: 160.17300
  • Catalog: Others
  • Density: 1.2 g/cm3
  • Boiling Point: 350.7ºC at 760 mmHg
  • Melting Point: 204-206 °C(lit.)
  • Flash Point: 165.9ºC

DNA-PK Substrate

DNA-PK Substrate is a biological active peptide. (A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11–24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activityPyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

  • CAS Number: 146064-85-9
  • MF: C82H123N19O24
  • MW: 1758.97
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Ethoxy-2,6-difluoro-DL-phenylalanine

3-Ethoxy-2,6-difluoro-DL-phenylalanine is an alanine derivative[1].

  • CAS Number: 1260007-97-3
  • MF: C11H13F2NO3
  • MW: 245.22300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 219-221℃
  • Flash Point: N/A

Zearalanone

Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system[1].

  • CAS Number: 5975-78-0
  • MF: C18H24O5
  • MW: 320.380
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 576.8±50.0 °C at 760 mmHg
  • Melting Point: 184-186ºC
  • Flash Point: 209.2±23.6 °C

1L-EPI-2-INOSOSE

1L-epi-2-Inosose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 33471-33-9
  • MF: C6H10O6
  • MW: 178.140
  • Catalog: Others
  • Density: 2.0±0.1 g/cm3
  • Boiling Point: 368.6±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 190.9±24.4 °C

L-Palmitoylcarnitine

L-Palmitoylcarnitine is a fatty acid metabolite.

  • CAS Number: 2364-67-2
  • MF: C23H45NO4
  • MW: 399.60800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Luteolin-7-O-glucuronide

Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.

  • CAS Number: 29741-10-4
  • MF: C21H18O12
  • MW: 462.360
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 892.5±65.0 °C at 760 mmHg
  • Melting Point: 242-244℃
  • Flash Point: 315.2±27.8 °C

somatorelin

Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary. Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2.

  • CAS Number: 83930-13-6
  • MF: C215H358N72O66S
  • MW: 5039.65
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Selcopintide

Selcopintide (Cpne7-DP) consists of a synthetic peptide corresponding to the 10 amino acid residue 344-353 fragment of the hCPNE7 protein. Selcopintide promotes dentin regeneration in dentinal defects of various degrees and that the regenerated hard tissue demonstrates the characteristics of true dentin[1].

  • CAS Number: 2130912-34-2
  • MF: C62H105N21O15
  • MW: 1384.63
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2R,4S)-Boc-D-Pro(4-N3)-OH

(2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide[1].

  • CAS Number: 132622-77-6
  • MF: C10H16N4O4
  • MW: 256.25800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4,4'-[(1E)-5-Hydroxy-1-heptene-1,7-diyl]diphenol

1,7-Bis(4-hydroxyphenyl)hept-6-en-3-ol (Compound M32) is a natural product that can be isolated from Curcuma longa L.[1].

  • CAS Number: 1083195-05-4
  • MF: C19H22O3
  • MW: 298.376
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 540.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 253.9±24.7 °C

dl-o-methylserine

2-Amino-3-methoxypropanoic acid is a serine derivative[1].

  • CAS Number: 19794-53-7
  • MF: C4H9NO3
  • MW: 119.119
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 260.6±30.0 °C at 760 mmHg
  • Melting Point: 210-215ºC
  • Flash Point: 111.4±24.6 °C

Fmoc-Lys(dansyl)-OH

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-lysine is a lysine derivative[1].

  • CAS Number: 118584-90-0
  • MF: C33H35N3O6S
  • MW: 601.71200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Naginata ketone

Naginata ketone is an aroma-active compound that can be isolated from Elsholtzia splendens[1].

  • CAS Number: 6138-88-1
  • MF: C10H12O2
  • MW: 164.20
  • Catalog: Others
  • Density: 1.0005 g/cm3 (30℃)
  • Boiling Point: 112-116℃ (20 Torr)
  • Melting Point: 145-146℃
  • Flash Point: N/A

Tenulin

Tenulin is a sesquiterpene lactone. Tenulin can be isolated from Helenium amarum[1].

  • CAS Number: 19202-92-7
  • MF: C16H20O5
  • MW: 292.32700
  • Catalog: Others
  • Density: 1.263g/cm3
  • Boiling Point: 490.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 180.3ºC