5-hydroxy Thiabendazole

Modify Date: 2025-08-22 12:50:13

5-hydroxy Thiabendazole Structure
5-hydroxy Thiabendazole structure
Common Name 5-hydroxy Thiabendazole
CAS Number 948-71-0 Molecular Weight 217.25
Density 1.535g/cm3 Boiling Point 525.6ºC at 760mmHg
Molecular Formula C10H7N3OS Melting Point N/A
MSDS Chinese USA Flash Point 271.7ºC
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of 5-hydroxy Thiabendazole


5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure[1].

 Names

Name 5-Hydroxy Thiabendazole
Synonym More Synonyms

 5-hydroxy Thiabendazole Biological Activity

Description 5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure[1].
Related Catalog
References

[1]. STONE OJ, et al. COMPARISON OF THIABENDAZOLE AND 5-HYDROXY-THIABENDAZOLE (FOR ANTHELMINTIC EFFECT). J Invest Dermatol. 1965 Aug;45:132-3.  

 Chemical & Physical Properties

Density 1.535g/cm3
Boiling Point 525.6ºC at 760mmHg
Molecular Formula C10H7N3OS
Molecular Weight 217.25
Flash Point 271.7ºC
Exact Mass 217.03100
PSA 90.04000
LogP 2.39200
Index of Refraction 1.783
Storage condition 0-6°C

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H400
Precautionary Statements P273
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn,N
Risk Phrases 22-50/53
Safety Phrases 60-61
RIDADR UN 3077
Packaging Group III
Hazard Class 9
HS Code 2934999090

 Synthetic Route

~%

5-hydroxy Thiabendazole Structure

5-hydroxy Thiab...

CAS#:948-71-0

Literature: Xenobiotica, , vol. 26, # 7 p. 765 - 778

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles16

More Articles
Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.

J. AOAC Int. 98(1) , 230-47, (2015)

Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using ...

Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells.

Chem. Biol. Interact. 127(2) , 109-24, (2000)

Thiabendazole (TBZ), an anthelmintic and fungicide benzimidazole, was recently demonstrated to be extensively metabolized by cytochrome P450 (CYP) 1A2 in man and rabbit, yielding 5-hydroxythiabendazol...

In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions.

Drug Metab. Dispos. 37 , 1286-1294, (2009)

Thiabendazole (TBZ) and its major metabolite 5-hydroxythiabendazole (5OH-TBZ) were screened for potential time-dependent inhibition (TDI) against CYP1A2. Screen assays were carried out in the absence ...

 Synonyms

2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-ol
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

5-hydroxy Thiabendazole suppliers

5-hydroxy Thiabendazole price

Related Compounds: More...
5-Hydroxy Thiabendazole
1391052-65-5
5-Hydroxy Thiabendazole
2318-79-8
5-Hydroxy Thiabendazole
962-28-7
5-Hydroxy-2-methylbenzamide
1243287-58-2
5-[(Hydroxy)bis[p-(dimethylamino)phenyl]methyl]-4-chloro-3-methyl-1-phenyl-2-pyrazoline 2-oxide
20192-10-3
5-Hydroxy-6,8-dimethyl-7-[(4-O-methyl-D-glucopyranosyl)oxy]-4H-1-benzopyran-4-one
21754-21-2
5-[hydroxy-(4-nitrophenoxy)phosphoryl]pentanoic acid
107099-17-2
5-Hydroxy-2-(4-nitrophenylazo)pyridine
35771-41-6
5-hydroxy-3-phenyl-5-(1,2,3,4-tetrahydroxybutyl)-1,3-thiazolidine-2-thione
113340-98-0
(2S,4R)-1-[(2S)-3,3-dimethyl-2-[[2-[2-(4-piperidylmethoxy)ethoxy]acetyl]amino]butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
2713621-46-4
(2S,4R)-1-[(2S)-3,3-dimethyl-2-[[2-[2-(4-piperidyloxy)ethoxy]acetyl]amino]butanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methylthiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
2378260-92-3
tert-butyl N-(2-azidoethyl)-N-[2-[2-[2-[3-[[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]amino]-3-oxo-propoxy]ethoxy]ethoxy]ethyl]carbamate
2415736-81-9
tert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-N-[4-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]-4-oxo-butyl]carbamate
2415732-85-1
2-[2-[2-[2-[[(1S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methylthiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidine-1-carbonyl]-2,2-dimethyl-propyl]amino]-2-oxo-ethoxy]ethoxy]ethoxy]acetic acid
2172820-10-7
3-[2-[2-[2-[[(1S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methylthiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidine-1-carbonyl]-2,2-dimethyl-propyl]amino]ethoxy]ethoxy]ethoxy]propanoic acid
2730971-77-2
4-[Amino(cyclopropyl)methyl]-2-methyl-5-(propan-2-yl)phenol
2167956-12-7
5-Cyclopropyl-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2,4,6-tetraene-3-carboxylic acid
2172012-11-0
(2S,4R)-4-hydroxy-1-[(2S)-2-[3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoylamino]-3,3-dimethyl-butanoyl]-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
2940861-93-6
2,9-Dicyclopropyl-1-oxa-5,9-diazaspiro[5.5]undecane
2172269-40-6