5-hydroxy Thiabendazole

Modify Date: 2024-01-09 21:08:02

5-hydroxy Thiabendazole structure	Common Name	5-hydroxy Thiabendazole
	CAS Number	948-71-0	Molecular Weight	217.25
	Density	1.535g/cm3	Boiling Point	525.6ºC at 760mmHg
	Molecular Formula	C₁₀H₇N₃OS	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	271.7ºC
	Symbol	GHS07, GHS09	Signal Word	Warning

Use of 5-hydroxy Thiabendazole

5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure[1].

Name	5-Hydroxy Thiabendazole
Synonym	More Synonyms

Description	5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure[1].
Related Catalog	Research Areas >> Others
References	[1]. STONE OJ, et al. COMPARISON OF THIABENDAZOLE AND 5-HYDROXY-THIABENDAZOLE (FOR ANTHELMINTIC EFFECT). J Invest Dermatol. 1965 Aug;45:132-3.

Density	1.535g/cm3
Boiling Point	525.6ºC at 760mmHg
Molecular Formula	C₁₀H₇N₃OS
Molecular Weight	217.25
Flash Point	271.7ºC
Exact Mass	217.03100
PSA	90.04000
LogP	2.39200
Index of Refraction	1.783
Storage condition	0-6°C

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H400
Precautionary Statements	P273
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn,N
Risk Phrases	22-50/53
Safety Phrases	60-61
RIDADR	UN 3077
Packaging Group	III
Hazard Class	9
HS Code	2934999090

Thiabendazole

CAS#:148-79-8

5-hydroxy Thiab...

CAS#:948-71-0

Literature: Xenobiotica, , vol. 26, # 7 p. 765 - 778

Precursor 1
CAS#:148-79-8 Thiabendazole
DownStream 1
CAS#:962-28-7 5-Hydroxy Thiab...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.

J. AOAC Int. 98(1) , 230-47, (2015)

Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using ...

Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells.

Chem. Biol. Interact. 127(2) , 109-24, (2000)

Thiabendazole (TBZ), an anthelmintic and fungicide benzimidazole, was recently demonstrated to be extensively metabolized by cytochrome P450 (CYP) 1A2 in man and rabbit, yielding 5-hydroxythiabendazol...

In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions.

Drug Metab. Dispos. 37 , 1286-1294, (2009)

Thiabendazole (TBZ) and its major metabolite 5-hydroxythiabendazole (5OH-TBZ) were screened for potential time-dependent inhibition (TDI) against CYP1A2. Screen assays were carried out in the absence ...

2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-ol