29741-10-4

29741-10-4 structure

Name: Luteolin-7-O-glucuronide
Chemical Name: luteolin 7-O-β-D-glucosiduronic acid
CAS Number: 29741-10-4
Molecular Formula: C₂₁H₁₈O₁₂
Molecular Weight: 462.360
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-12-23 18:59:03
Modify Date: 2024-01-02 16:59:40
Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.

Name	luteolin 7-O-β-D-glucosiduronic acid
Synonyms	(2S,3S,4S,5R)-6-[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid luteolin 7-O-beta-D-glucosiduronic acid Luteolin-7-glucuronide 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranuronosyloxy)-5-hydroxy- Luteolin 7-O-glucuronide

Description	Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.
Related Catalog	Research Areas >> Others Natural Products >> Flavonoids
Target	MMP-1:17.63 μM (IC50) MMP-3:7.99 μM (IC50) MMP-8:11.42 μM (IC50) MMP-9:12.85 μM (IC50) MMP13:0.03 μM (IC50)
References	[1]. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911.