DNA-PK Substrate
Modify Date: 2024-02-04 18:05:45
DNA-PK Substrate structure
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Common Name | DNA-PK Substrate | ||
|---|---|---|---|---|
| CAS Number | 146064-85-9 | Molecular Weight | 1758.97 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C82H123N19O24 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DNA-PK SubstrateDNA-PK Substrate is a biological active peptide. (A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11–24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activityPyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.) |
| Name | DNA-PK Substrate |
|---|
| Description | DNA-PK Substrate is a biological active peptide. (A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11–24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activityPyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.) |
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| Related Catalog |
| Molecular Formula | C82H123N19O24 |
|---|---|
| Molecular Weight | 1758.97 |