Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Antidesmone

Antidesmone is a isoquinoline alkaloid that can be isolated from Antidesma membranaceum[1].

  • CAS Number: 222629-77-8
  • MF: C19H29NO3
  • MW: 319.44
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 468.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 237.0±28.7 °C

Ac-Ile-Glu-Thr-Asp-AMC

Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity[1].

  • CAS Number: 348079-17-4
  • MF: C31H41N5O12
  • MW: 675.683
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1157.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 653.9±34.3 °C

Propan-1-amine-d5 hydrochloride

Propan-1-amine-dd5 hydrochloride is the deuterium labeled Propan-1-amine hydrochloride[1].

  • CAS Number: 1398065-66-1
  • MF: C3H5D5ClN
  • MW: 100.60
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

11-(4-(Hydroxy(oxido)amino)phenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical[1].

  • CAS Number: 82408-04-6
  • MF: C21H21N3O3
  • MW: 363.41000
  • Catalog: Others
  • Density: 1.31g/cm3
  • Boiling Point: 565.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 295.8ºC

Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves[1].

  • CAS Number: 143061-65-8
  • MF: C36H36O18
  • MW: 756.660
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 1092.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 342.0±27.8 °C

M-MoDE-A (2)

M-MoDE-A (2) is a bifunctional small molecule that mediates the degradation of extracellular proteins through the asialoglycoprotein receptor (ASGPR).

  • CAS Number: 2378837-56-8
  • MF: C78H119FN12O34
  • MW: 1787.84
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Calcium Green 1AM

Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases[1].

  • CAS Number: 186501-28-0
  • MF: C59H53Cl2N3O26
  • MW: 1290.963
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 1145.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 646.4±34.3 °C

torachrysone

Torachrysone (Nakahalene; Trachrysone), a naphthalene, can be isolated from Cassia tora L[1].

  • CAS Number: 22649-04-3
  • MF: C14H14O4
  • MW: 246.259
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 457.1±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 176.3±20.8 °C

DL001

DL001, a FKBP12-dependent rapamycin analog, is a selective mechanistic Target Of Rapamycin Complex 1 (mTORC1) inhibitor with an IC50 of 74.9 pM. In cells, DL001 efficiently represses elevated mTORC1 activity and restores normal gene expression to cells lacking a functional tuberous sclerosis complex. DL001 inhibits mTORC1 signaling without impairing glucose homeostasis and with substantially reduced and no side effects on lipid metabolism and the immune system in vivo in C57BL/6J mice[1].

  • CAS Number: 909387-87-7
  • MF: C49H75NO12
  • MW: 870.12
  • Catalog: mTOR
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Zapalog

Zapalog is a photocleavable small-molecule heterodimerizer that can be used to repeatedly initiate, and instantaneously terminate, a physical interaction between two target proteins. Zapalog dimerizes any two proteins tagged with the FKBP and DHFR domains until exposure to light causes its photolysis[1].

  • CAS Number: 1708091-24-0
  • MF: C58H73N7O15
  • MW: 1108.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hulupinic acid

Hulupinic acid is a prominent oxidation product of hop acids[1].

  • CAS Number: 1891-42-5
  • MF: C15H20O4
  • MW: 264.31700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-4-Bromo-L-beta-phenylalanine

(R)-3-(4-Bromophenyl)-3-((tert-butoxycarbonyl)amino)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 261380-20-5
  • MF: C14H18BrNO4
  • MW: 344.201
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 479.1±40.0 °C at 760 mmHg
  • Melting Point: 142.1ºC
  • Flash Point: 243.6±27.3 °C

Fmoc-Glu-O-2-PhiPr

Fmoc-Glu-O-2-PhiPr is a glutamic acid derivative[1].

  • CAS Number: 207305-97-3
  • MF: C29H29NO6
  • MW: 487.54400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

α-cypermethrin

Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is an effective insecticide against house flies[1].

  • CAS Number: 67375-30-8
  • MF: C22H19Cl2NO3
  • MW: 416.297
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 511.3±50.0 °C at 760 mmHg
  • Melting Point: 78-81ºC
  • Flash Point: 263.0±30.1 °C

6PPD-quinone-D5

6PPD-quinone-d5 is the deuterium labeled 6PPD-quinone[1].

  • CAS Number: 2750119-14-1
  • MF: C18H17D5N2O2
  • MW: 303.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isobutyl Hydrogen Phthalate

Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium.

  • CAS Number: 30833-53-5
  • MF: C12H14O4
  • MW: 222.237
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 356.6±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 135.0±16.7 °C

5-Vinylcytidine

5-Vinylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

  • CAS Number: 1846584-62-0
  • MF: C11H15N3O5
  • MW: 269.25
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-IDO1-IN-5

(S)-IDO1-IN-5 is the S-isomer of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].

  • CAS Number: 2166616-76-6
  • MF: C23H25FN2O3
  • MW: 396.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Arbutin

Arbutin(β-Arbutin) is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos; inhibits tyrosinase and thus prevents the formation of melanin.IC50 value:Target: tyrosinase

  • CAS Number: 497-76-7
  • MF: C12H16O7
  • MW: 272.251
  • Catalog: Tyrosinase
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 561.6±50.0 °C at 760 mmHg
  • Melting Point: 195-198 °C
  • Flash Point: 293.4±30.1 °C

3-(DANSYLAMINO)PHENYLBORONIC ACID

3-(Dansylamino)phenylboronic acid, a phenylboronic acid derivative, can be used for the glucose detection[1].

  • CAS Number: 75806-94-9
  • MF: C18H19BN2O4S
  • MW: 370.23000
  • Catalog: Others
  • Density: 1.39g/cm3
  • Boiling Point: 599.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 316.3ºC

Thevetin B

Thevetin B (compound 1) is a betalain isolated from Thevetia peruviana[1].

  • CAS Number: 27127-79-3
  • MF: C42H66O18
  • MW: 858.963
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 1008.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 298.1±27.8 °C

spiranthesol

Spiranthesol is an active compound. Spiranthesol can be isolated from the aerial parts of Spiranthes sinensis(Pers.) [1].

  • CAS Number: 125263-69-6
  • MF: C40H42O6
  • MW: 618.75800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Deoxystrigol

5-Deoxystrigol is a potent striga germination stimulant[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N,N,N-Triethylethanaminiumfluoriddihydrat

Tetraethylammonium fluoride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 665-46-3
  • MF: C8H24FNO2
  • MW: 185.280
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BCDA

Esterase chromogenic substrate-1 is a chromogenic substrate of esterase used to detect the activity of esterase.

  • CAS Number: 3252-36-6
  • MF: C10H7BrClNO2
  • MW: 288.52500
  • Catalog: Dye Reagents
  • Density: 1.721g/cm3
  • Boiling Point: 429.3ºC at 760mmHg
  • Melting Point: 107 °C(dec.)
  • Flash Point: 213.4ºC

Seleno-L-cysteine

Selenocysteine is aselenocysteine.

  • CAS Number: 10236-58-5
  • MF: C3H7NO2Se
  • MW: 168.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 440.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 220.0±28.7 °C

Ala-Ala-Pro-pNA

Ala-Ala-Pro-pNA is a tripeptide, including chromophoric amino acids Pro-pNA. Ala-Ala-Pro-pNA is targeted by tripeptidyl aminopeptidase (SM-TAP)[1].

  • CAS Number: 99524-09-1
  • MF: C17H23N5O5
  • MW: 377.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Simetryn

Simetryn is a herbicide with the LC50 of 16.9-3.70 mg/L (79.3-17.4 microM.

  • CAS Number: 1014-70-6
  • MF: C8H15N5S
  • MW: 213.303
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 302.5±25.0 °C at 760 mmHg
  • Melting Point: 82-83°C
  • Flash Point: 136.8±23.2 °C

ATTO 680 NHS ester

ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.

  • CAS Number: 1537182-26-5
  • MF: C31H34N4O8S
  • MW: 622.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Citric acid-2,4-13C2

Citric acid-2,4-13C2 (Sodium Lauryl Sulfate) is a labeled citric acid. Citric acid is found in many fruits and vegetables, especially citrus fruits. It participates in biological processes in the body, such as the citric acid cycle.

  • CAS Number: 121633-50-9
  • MF: C6H8O7
  • MW: 194.10900
  • Catalog: Others
  • Density: 1.762g/cm3
  • Boiling Point: N/A
  • Melting Point: 153-159ºC(lit.)
  • Flash Point: N/A