1708091-24-0

1708091-24-0 structure

Name: Zapalog
Chemical Name: Zapalog
CAS Number: 1708091-24-0
Molecular Formula: C₅₈H₇₃N₇O₁₅
Molecular Weight: 1108.24
Catalog: Research Areas Others
Create Date: 2019-10-07 22:52:52
Modify Date: 2025-09-20 17:54:58
Zapalog is a photocleavable small-molecule heterodimerizer that can be used to repeatedly initiate, and instantaneously terminate, a physical interaction between two target proteins. Zapalog dimerizes any two proteins tagged with the FKBP and DHFR domains until exposure to light causes its photolysis[1].

Name	Zapalog

Description	Zapalog is a photocleavable small-molecule heterodimerizer that can be used to repeatedly initiate, and instantaneously terminate, a physical interaction between two target proteins. Zapalog dimerizes any two proteins tagged with the FKBP and DHFR domains until exposure to light causes its photolysis[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Gutnick A, et al. The light-sensitive dimerizer zapalog reveals distinct modes of immobilization for axonal mitochondria. Nat Cell Biol. 2019 Jun;21(6):768-777.

Molecular Formula	C₅₈H₇₃N₇O₁₅
Molecular Weight	1108.24