Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Deacetyl ganoderic acid F

Deacetyl Ganoderic Acid F is a 7-anostane triterpenoid from Ganoderma lucidum.

  • CAS Number: 100665-44-9
  • MF: C30H40O8
  • MW: 528.634
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 707.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 395.9±29.4 °C

Glycoside St-J

Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents [1].

  • CAS Number: 203513-88-6
  • MF: C54H86O23
  • MW: 1103.25
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Obestatin (human) trifluoroacetate salt

Obestatin(human) is an endogenous peptide derived from the same prepropeptide as ghrelin. Obestatin(human) suppresses food intake and reduce body weight-gain in rats.

  • CAS Number: 1081110-72-6
  • MF: C116H176N32O33
  • MW: 2546.833
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 2616.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1536.0±34.3 °C

H-Lys-Arg-OH acetate salt

H-Lys-Arg-OH is a biologically active peptide.

  • CAS Number: 29586-66-1
  • MF: C12H26N6O3
  • MW: 302.37300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

16-o-acetyldarutigenol

16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis[1].

  • CAS Number: 1188282-01-0
  • MF: C22H36O4
  • MW: 364.52
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 490.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 162.3±22.2 °C

Lurasidone metabolite 14326

Lurasidone metabolite 14326 is a metabolite of Lurasidone, which is a atypical antipsychotic compound.

  • CAS Number: 186204-33-1
  • MF: C28H36N4O3S
  • MW: 508.68
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

10-Hydroxyaloin B

10-Hydroxyaloin B is a bioactive oxanthrone based on the aloin skeleton[1].

  • CAS Number: 134863-92-6
  • MF: C21H22O10
  • MW: 434.39
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cuniloside B

Cuniloside B (Eucalmaidin E) is a non-volatile glucose monoterpene ester. Cuniloside B can be used as a fragrance additive[1].

  • CAS Number: 1187303-40-7
  • MF: C26H40O10
  • MW: 512.590
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 680.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 221.3±25.0 °C

Ganhuangemin

2′,3,5,6′,7-Pentahydroxyflavanone (compound 4) is a flavonoid compound isolated from Scutellaria baicalensis roots[1].

  • CAS Number: 80366-15-0
  • MF: C15H12O7
  • MW: 304.25
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 713.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 273.8±26.4 °C

Bucetin

Bucetin (3-Hydroxy-p-butyrophenetidide) is an analgesic and antipyretic compound.

  • CAS Number: 1083-57-4
  • MF: C12H17NO3
  • MW: 223.26800
  • Catalog: Others
  • Density: 1.151g/cm3
  • Boiling Point: 433.5ºC at 760 mmHg
  • Melting Point: 160ºC
  • Flash Point: 216ºC

5-carboxypentan-1-olate-d6 sodium

5-carboxypentan-1-olate-d6 (sodium) is the deuterium labeled Sodium 5-carboxypentan-1-olate[1].

  • CAS Number: 1219794-58-7
  • MF: C6H5D6NaO3
  • MW: 160.17600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-[[4-[(2-Amino-4-Oxo-1H-Pteridin-6-Yl)Methyl-Methylamino]Benzoyl]Amino]Pentanedioic Acid

Methopterin inhibits osteoclasts proliferation. Methopterin inhibits the activation and bone resorption function of osteoclasts, and induced osteoclasts apoptosis[1].

  • CAS Number: 2410-93-7
  • MF: C20H21N7O6
  • MW: 455.42400
  • Catalog: Inflammation/Immunology
  • Density: 1.61g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-ILE-BETANA

L-Isoleucine β-naphthylamide is an isoleucine derivative[1].

  • CAS Number: 732-84-3
  • MF: C16H20N2O
  • MW: 256.34300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Trp-Arg-OH · 2 HCl

H-Trp-Arg-OH is a biologically active peptide.

  • CAS Number: 88831-09-8
  • MF: C17H24N6O3
  • MW: 360.41100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Acetyl-S-(2-cyanoethyl)-L-cysteine-d3

N-Acetyl-S-(2-cyanoethyl)-L-cysteine-d3 is the deuterium labeled N-Acetyl-S-(2-cyanoethyl)-L-cysteine[1].

  • CAS Number: 1260619-59-7
  • MF: C8H9D3N2O3S
  • MW: 219.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

14:0 EPC chloride

14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery[1].

  • CAS Number: 186492-53-5
  • MF: C38H77ClNO8P
  • MW: 742.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Sar-Opfp

Fmoc-Sar-OPfp is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 159631-29-5
  • MF: C24H16F5NO4
  • MW: 477.38000
  • Catalog: Others
  • Density: 1.434g/cm3
  • Boiling Point: 549.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.1ºC

(S)-BAY73-6691

(S)-BAY 73-6691 is the inactive isomer of BAY 73-6691 (HY-104028), and can be used as an experimental control. BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor[1].

  • CAS Number: 794568-91-5
  • MF: C15H12ClF3N4O
  • MW: 356.73
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jujuboside B

Jujuboside B is one of the major bioactive constituents isolated from Zizyphus jujuba. Jujuboside B can inhibit platelet aggregation[1].

  • CAS Number: 55466-05-2
  • MF: C52H84O21
  • MW: 1045.211
  • Catalog: Cardiovascular Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 228-231ºC
  • Flash Point: N/A

MAT2A-IN-5

MAT2A-IN-5 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-5 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-5 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 1)[1].

  • CAS Number: 2756458-55-4
  • MF: C17H12ClF3N2O
  • MW: 352.74
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

cetraxate

Cetraxate is an orally active antiulcer Drug. Cetraxate increases the blood flow of gastric mucosal. Cetraxate increases the eradication of Helicobacter pylori in smokers when in combination with Omeprazole (HY-B0113),Amoxicillin (HY-B0467A), and Clarithromycin (HY-17508) [1].

  • CAS Number: 34675-84-8
  • MF: C17H23NO4
  • MW: 305.36900
  • Catalog: Infection
  • Density: 1.182g/cm3
  • Boiling Point: 480.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 244.6ºC

uperolein

Uperolein is a physalaemin-like endecapeptide, produced in the skin of Uperoleia rugosa and Uperoleia marmorata. Uperolein has a spasmodic effect on both the gastrointestinal tract and longitudinal muscles[1][2][3].

  • CAS Number: 55601-63-3
  • MF: C57H79N13O16S
  • MW: 1234.380
  • Catalog: Neurological Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1720.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 994.3±34.3 °C

MilatuzuMab

Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ilicic acid

Ilicic acid is a sesquiterpene lactones. Ilicic acid can be isolated Ambrosia camphorat[1].

  • CAS Number: 4586-68-9
  • MF: C15H24O3
  • MW: 252.349
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 399.4±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 209.5±19.7 °C

dl-threo-3-phenylserine hydrate

DL-3-Phenylserine hydrate is a serine derivative[1].

  • CAS Number: 207605-47-8
  • MF: C9H13NO4
  • MW: 199.20400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 186ºC (dec.)(lit.)
  • Flash Point: N/A

N-[(Benzyloxy)carbonyl]-D-alloisoleucine

Benzyloxycarbonyl-D-alloisoleucine is an isoleucine derivative[1].

  • CAS Number: 55723-45-0
  • MF: C14H19NO4
  • MW: 265.305
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 442.8±38.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 221.6±26.8 °C

Sanggenol A

Sanggenol A acts as a dual inhibitor of nitrofuranone reduction mediated by the intestinal microbial nitrification reductases EcNfsA and EcNfsB. In addition, Sanggenol A is also an effective inhibitor of intestinal bacterial β-glucuronidase[1].

  • CAS Number: 174423-30-4
  • MF: C25H28O6
  • MW: 424.486
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 683.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 234.0±25.0 °C

(R)-2,3-Dihydroxypropanal-3-13C

(R)-2,3-Dihydroxypropanal-3-13C is the 13C labeled (R)-2,3-Dihydroxypropanal[1].

  • CAS Number: 478529-50-9
  • MF: C3H6O3
  • MW: 91.07060
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,7-Dihydrohomoerysotrine

2,7-Dihydrohomoerysotrine is an alkaloid that can be found in Dysoxylum[1].

  • CAS Number: 51095-85-3
  • MF: C20H27NO3
  • MW: 329.43
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 458.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 132.0±25.9 °C

DSPE-PEG(2000)-Amine

DSPE-PEG(2000)-Amine is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents[1][2][3].

  • CAS Number: 474922-26-4
  • MF: (C2H4O)nC44H87N2O10P.NH3
  • MW: 896.226
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A