34675-84-8

34675-84-8 structure

Name: cetraxate
Chemical Name: cetraxate
CAS Number: 34675-84-8
Molecular Formula: C₁₇H₂₃NO₄
Molecular Weight: 305.36900
Catalog: Research Areas Infection
Create Date: 2018-08-24 11:56:44
Modify Date: 2025-08-26 13:46:38
Cetraxate is an orally active antiulcer Drug. Cetraxate increases the blood flow of gastric mucosal. Cetraxate increases the eradication of Helicobacter pylori in smokers when in combination with Omeprazole (HY-B0113),Amoxicillin (HY-B0467A), and Clarithromycin (HY-17508) [1].

Name	cetraxate
Synonyms	Cetraxate [INN] Cetraxate 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid 4'-(2-carboxyethyl)phenyl.trans-4-aminomethylcyclohexane carboxylate trans-4-(((4-(Aminomethyl)cyclohexyl)carbonyl)oxy)benzenepropanoic acid Cetraxato [INN-Spanish] 3-[4-({[4-(aminomethyl)cyclohexyl]carbonyl}oxy)phenyl]propanoic acid Cetraxatum [INN-Latin] p-hydroxyhydrocinnamic acid trans-(4-aminomethyl)cyclohexanecarboxylate

Description	Cetraxate is an orally active antiulcer Drug. Cetraxate increases the blood flow of gastric mucosal. Cetraxate increases the eradication of Helicobacter pylori in smokers when in combination with Omeprazole (HY-B0113),Amoxicillin (HY-B0467A), and Clarithromycin (HY-17508) [1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Kamada T, et al. Cetraxate, a mucosal protective agent, combined with omeprazole, amoxycillin, and clarithromycin increases the eradication rate of helicobacter pylori in smokers. Aliment Pharmacol Ther. 2000 Aug;14(8):1089-94.

Density	1.182g/cm3
Boiling Point	480.9ºC at 760mmHg
Molecular Formula	C₁₇H₂₃NO₄
Molecular Weight	305.36900
Flash Point	244.6ºC
Exact Mass	305.16300
PSA	89.62000
LogP	3.07460
Index of Refraction	1.551

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA8340500

CHEMICAL NAME :: Benzenepropanoic acid, 4-(((4-(aminomethyl)cyclohexyl)carbonyl)oxy)-, trans-

CAS REGISTRY NUMBER :: 34675-84-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C17-H23-N-O4

MOLECULAR WEIGHT :: 305.41

WISWESSER LINE NOTATION :: L6TJ AVOR D2VQ& D1Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 716 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1503 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 345 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1520 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 681 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 19,323,1980

HS Code	2922509090

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

34675-84-8	27724-96-5
27725-13-9	2504203-19-2
2504202-71-3	2913572-50-4
2734745-79-8	2633633-50-6
2364439-35-8	2137549-20-1
2226739-31-5	1217471-56-1
2137738-28-2