DSPE-PEG(2000)-Amine

Modify Date: 2024-01-11 08:10:09

DSPE-PEG(2000)-Amine Structure
DSPE-PEG(2000)-Amine structure
Common Name DSPE-PEG(2000)-Amine
CAS Number 474922-26-4 Molecular Weight 896.226
Density N/A Boiling Point N/A
Molecular Formula (C2H4O)nC44H87N2O10P.NH3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DSPE-PEG(2000)-Amine


DSPE-PEG(2000)-Amine is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents[1][2][3].

 Names

Name 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[aMino(polyethylene glycol)-2000] (aMMoniuM salt)
Synonym More Synonyms

 DSPE-PEG(2000)-Amine Biological Activity

Description DSPE-PEG(2000)-Amine is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents[1][2][3].
Related Catalog
In Vitro DSPE-PEG(2000)-Amine is coated on the surface of the fluorescein diacetate (FDA) nanocrystals to provide a interface for the antibody coupling. The FDA[DSPE-PEG(2000)Amine]-modified biolabels have a highly stable colloidal suspension with minimized nonspecific interactions. The adsorbed DSPE-PEG(2000)Amine layer causes the FDA nanocrystals to disperse in water and prevents their aggregation, hence conferring colloidal stability[3].
References

[1]. Feilong Sun, et al. A Mixed Micelle Formulation for Oral Delivery of Vitamin K. Pharm Res. 2016 Sep;33(9):2168-79.

[2]. Brian R Sloat, et al. In Vitro and in Vivo Anti-Tumor Activities of a Gemcitabine Derivative Carried by Nanoparticles. Int J Pharm. 2011 May 16;409(1-2):278-88.

[3]. Cangel Pui-yee Chan, et al. Nanocrystal Biolabels With Releasable Fluorophores for Immunoassays. Anal Chem. 2004 Jul 1;76(13):3638-45.

 Chemical & Physical Properties

Molecular Formula (C2H4O)nC44H87N2O10P.NH3
Molecular Weight 896.226
Exact Mass 895.662598
Storage condition -20°C

 Safety Information

Hazard Class 6.1

 Synonyms

Octadecanoic acid, 1-[[[[2-[[[2-(2-aminoethoxy)ethoxy]carbonyl]amino]ethoxy]hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, ammonium salt
35-Amino-24-hydroxy-24-oxido-18,29-dioxo-19,23,25,30,33-pentaoxa-28-aza-24λ5-phosphapentatriacontan-21-yl octadecanoate ammoniate (1:1)
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Price: ¥1000/10 mg

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