α-Synuclein (61-75) is the 61-75 fragment of α-Synuclein. α-Synuclein is an abundant neuronal protein that is highly enriched in presynaptic nerve terminals. α-Synuclein is a potential biomarker for Parkinson's disease (PD)[1][2].
(2S,4S)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].
Quercetin 5,3′-dimethyl ether is a kind of flavonoid. Quercetin 5,3′-dimethyl ether can be isolated from Combretum erythrophyllum (Combretaceae). Quercetin 5,3′-dimethyl ether has anti-inflammatory activity and antibacterial activity[1].
C-phycocyanin is a water-soluble protein pigment which is also widely used as an excellent nutrient supplement for human beings.
PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 µM and 1.8 µM in PC12 cells and PC12 nnr5 cells, respectively [1] .
Raloxifene Bismethyl Ether hydrochloride is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent[1].
Isosalvianolic acid C is a phenolic compound that can be found in Lavandula angustifolia Mill.. Isosalvianolic acid C can be used as antioxidant[1].
(Rac)-Phorbol-12-(2-methylbutyrate) is a nature product that could be isolated form croton oil[1].
Piperlotine A is an alkaloid isolated from Piper lolot, with potent antiplatelet aggregation activity[1].
Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid drugs. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells[1].
MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].
Clopidogrel-MP endo derivative-13C,d3 is the deuterium and 13C labeled Clopidogrel-MP endo derivative[1].
Dihydrolapachenole is a naturally occurring quinone[1].
3-O-Methylgalangin (Galangin 3-methyl ether) is a natural flavonoid compound from the rhizome of Alpinia officinarum (AO) with antibacterial activities, which also inhibits pancreatic lipase[1][2].
2,2-Dibromoacetamide is a class of disinfection by-product (DBP) in drinking water[1].
Boc-Val-Gly-Arg-βNA is a colorimetric substrate for plasminogen activator[1].
Acetate-d7 (ammonium) is the deuterium labeled Ammonium acetate[1].
Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, is used in aquaculture to control susceptible bacterial diseases[1].
Alglucosidase alfa is a hydrolytic lysosomal glycogen-specific recombinant human α-glucosidase product. Alglucosidase alfa can be used for Pompe disease research[1].
Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively[1].
Gageotetrin C is an antimicrobial peptide derived from the marine bacterium Bacillus subtilis. Gageotetrin C is more active against fungi (MIC value is 0.02-0.04 μM) [1].
Z-D-Nle-ONp is a leucine derivative[1].
Naproxcinod (Nitronaproxen) is the first in class of cyclooxygenase (COX)-inhibiting nitric oxide donators (CINODs). Naproxcinod shows analgesic and anti-inflammatory effects, it can be used for the research of osteoarthritis and inflammation[1][2][3].
Kaempferol inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK.
1,3-Propanediol is produced in nature by the fermentation of glycerol in microorganism[1].
1-Methylpyrrolidine is a methylated pyrollidine.
NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect[1][2].
Benzo[k]tetraphene-d14 is the deuterium labeled Benzo[k]tetraphene[1].
ELA-32(human) is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) exhibits no binding GPR15 and GPR25. ELA-32(human) activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) stimulates angiogenesis in HUVEC cells.
N-(Trimethylamine−boranecarbonyl)proline methyl ester is a proline derivative[1].