56491-86-2

56491-86-2 structure

Name: NOTA
Chemical Name: 2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid
CAS Number: 56491-86-2
Molecular Formula: C₁₂H₂₁N₃O₆
Molecular Weight: 303.31200
Catalog: Research Areas Cancer
Create Date: 2016-08-19 13:41:04
Modify Date: 2025-08-25 10:03:23
NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect[1][2].

Name	2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid
Synonyms	1H-1,4,7-Triazonine-1,4,7-triacetic acid,hexahydro NOTA 1,4,7-triazacyclononane-1,4,7-triacetic acid 1,4,7-triazacyclononane-N,N',N''-triacetic acid 67Ga-9N3

Description	NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Singh AN, et al. Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: signal amplification via multivalency. Bioconjug Chem. 2011;22(8):1650-1662. [2]. Liao AH, et al. Evaluation of 18F-labeled targeted perfluorocarbon-filled albumin microbubbles as a probe for microUS and microPET in tumor-bearing mice. Ultrasonics. 2013;53(2):320-327.

Hazard Codes	Xi

298-12-4

4730-54-5

56491-86-2

Literature: CONCAT LP, a California Limited Partnership Patent: US2005/112066 A1, 2005 ; Location in patent: Page/Page column 26 ;

79-08-3

58966-93-1

56491-86-2

Literature: Majkowska-Pilip; Bilewicz Journal of Inorganic Biochemistry, 2011 , vol. 105, # 2 p. 313 - 320

79-08-3

4730-54-5

56491-86-2

Literature: De Vos, Dirk E.; Bein, Thomas Journal of Organometallic Chemistry, 1996 , vol. 520, # 1-2 p. 195 - 200

58966-93-1

56491-86-2

Literature: Maheshwari, Vidhi; Dearling, Jason L.J.; Treves, S. Ted; Packard, Alan B. Inorganica Chimica Acta, 2012 , vol. 393, p. 318 - 323

Precursor 4
298-12-4 4730-54-5 79-08-3 58966-93-1
DownStream 0