(2S,4S)-H-L-Pro(4-N3)-OH

Modify Date: 2024-01-02 10:14:27

(2S,4S)-H-L-Pro(4-N3)-OH Structure
(2S,4S)-H-L-Pro(4-N3)-OH structure
Common Name (2S,4S)-H-L-Pro(4-N3)-OH
CAS Number 892128-58-4 Molecular Weight 192.60400
Density N/A Boiling Point N/A
Molecular Formula C5H9ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2S,4S)-H-L-Pro(4-N3)-OH


(2S,4S)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

 Names

Name (2S,4S)-4-Azido-2-carboxypyrrolidinium chloride

 (2S,4S)-H-L-Pro(4-N3)-OH Biological Activity

Description (2S,4S)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].
Related Catalog
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

 Chemical & Physical Properties

Molecular Formula C5H9ClN4O2
Molecular Weight 192.60400
Exact Mass 192.04100
PSA 99.08000
LogP 0.69536

 Synthetic Route

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(2S,4S)-H-L-Pro(4-N3)-OH Structure

(2S,4S)-H-L-Pro...

CAS#:892128-58-4

Literature: Klein, Larry L.; Li, Leping; Chen, Hui-Ju; Curty, Cynthia B.; Degoey, David A.; Grampovnik, David J.; Leone, Christina L.; Thomas, Sheela A.; Yeung, Clinton M.; Funk, Kenneth W.; Kishore, Vimal; Lundell, Edwin O.; Wodka, Dariusz; Meulbroek, Jon A.; Alder, Jeffrey D.; Nilius, Angela M.; Lartey, Paul A.; Plattner, Jacob J. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1677 - 1696

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(2S,4S)-H-L-Pro(4-N3)-OH Structure

(2S,4S)-H-L-Pro...

CAS#:892128-58-4

Literature: Klein, Larry L.; Li, Leping; Chen, Hui-Ju; Curty, Cynthia B.; Degoey, David A.; Grampovnik, David J.; Leone, Christina L.; Thomas, Sheela A.; Yeung, Clinton M.; Funk, Kenneth W.; Kishore, Vimal; Lundell, Edwin O.; Wodka, Dariusz; Meulbroek, Jon A.; Alder, Jeffrey D.; Nilius, Angela M.; Lartey, Paul A.; Plattner, Jacob J. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1677 - 1696

~%

(2S,4S)-H-L-Pro(4-N3)-OH Structure

(2S,4S)-H-L-Pro...

CAS#:892128-58-4

Literature: Klein, Larry L.; Li, Leping; Chen, Hui-Ju; Curty, Cynthia B.; Degoey, David A.; Grampovnik, David J.; Leone, Christina L.; Thomas, Sheela A.; Yeung, Clinton M.; Funk, Kenneth W.; Kishore, Vimal; Lundell, Edwin O.; Wodka, Dariusz; Meulbroek, Jon A.; Alder, Jeffrey D.; Nilius, Angela M.; Lartey, Paul A.; Plattner, Jacob J. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1677 - 1696

~%

(2S,4S)-H-L-Pro(4-N3)-OH Structure

(2S,4S)-H-L-Pro...

CAS#:892128-58-4

Literature: Nagel, Yvonne A.; Kuemin, Michael; Wennemers, Helma Chimia, 2011 , vol. 65, # 4 p. 264 - 267

~%

(2S,4S)-H-L-Pro(4-N3)-OH Structure

(2S,4S)-H-L-Pro...

CAS#:892128-58-4

Literature: Klein, Larry L.; Li, Leping; Chen, Hui-Ju; Curty, Cynthia B.; Degoey, David A.; Grampovnik, David J.; Leone, Christina L.; Thomas, Sheela A.; Yeung, Clinton M.; Funk, Kenneth W.; Kishore, Vimal; Lundell, Edwin O.; Wodka, Dariusz; Meulbroek, Jon A.; Alder, Jeffrey D.; Nilius, Angela M.; Lartey, Paul A.; Plattner, Jacob J. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1677 - 1696