Tigogenin

Modify Date: 2024-01-02 16:44:33

Tigogenin structure	Common Name	Tigogenin
	CAS Number	77-60-1	Molecular Weight	416.637
	Density	1.1±0.1 g/cm3	Boiling Point	516.6±20.0 °C at 760 mmHg
	Molecular Formula	C₂₇H₄₄O₃	Melting Point	202-204ºC
	MSDS	N/A	Flash Point	266.2±21.8 °C

Use of Tigogenin

Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid drugs. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells[1].

Name	(25R)-5.α.-Spirostan-3.β.-ol
Synonym	More Synonyms

Description	Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid drugs. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Zhou H, et al. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells. Mol Cell Endocrinol. 2007 May 30;270(1-2):17-22.

Density	1.1±0.1 g/cm3
Boiling Point	516.6±20.0 °C at 760 mmHg
Melting Point	202-204ºC
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.637
Flash Point	266.2±21.8 °C
Exact Mass	416.329041
PSA	38.69000
LogP	6.21
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.552

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WH1443500

CHEMICAL NAME :: 5-alpha-Spirostan-3-beta-ol, (25R)-

CAS REGISTRY NUMBER :: 77-60-1

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C27-H44-O3

MOLECULAR WEIGHT :: 416.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 29QKAZ "Toxins of Animal and Plant Origin, Proceedings International Symposium, 2nd, 1970," de Vries, A., and E. Kochva, eds., 3 vols., New York, Gordon and Breach Science Pub., 1971-73 Volume(issue)/page/year: 2,597,1972

Hazard Codes	Xi
RTECS	WH1443500
Hazard Class	2.3
HS Code	2932999099

Precursor 5
CAS#:512-04-9 Diosgenin CAS#:915-35-5 HECOGENIN ACETATE CAS#:690275-05-9 (E)-1-(tert-but... CAS#:110124-76-0 (25R)-5α-spiros...
CAS#:35959-24-1 (25R)-5α-spiros...
DownStream 4
CAS#:17916-30-2 Pregn-5-en-20-o... CAS#:571-20-0 5α-Androstane-3... CAS#:1169-20-6 (3β,5α)-20-Oxop... CAS#:1239-31-2 Epiandrosterone...

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5α-Spirostan-3β-ol, (25R)-

TIGOGENIN

Tsosarsasaprgein

(3β,5α,25R)-Spirostan-3-ol

MFCD00067287

Ticogenin

(25R)-5a-Spirostan-3b-ol

(25R)-5α-Spirostan-3β-ol

Sisalagenin

Trigonegenin B

EINECS 201-041-9

Spirostan-3-ol, (3β,5α,25R)-

BioBioPha
China
Product Name: Tigogenin
Price: ￥Inquiry/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Tigogenin
Price: ￥498.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Tigogenin
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Tigogenin suppliers

Price: ￥500/5 mg

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Tigogenin

Use of Tigogenin

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Tigogenin Biological Activity

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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