MIF-IN-6

Modify Date: 2025-09-25 18:32:36

MIF-IN-6 Structure
MIF-IN-6 structure
Common Name MIF-IN-6
CAS Number 2582758-61-8 Molecular Weight 385.78
Density N/A Boiling Point N/A
Molecular Formula C18H13ClFN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MIF-IN-6


MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].

 Names

Name MIF-IN-6

 MIF-IN-6 Biological Activity

Description MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].
Related Catalog
Target

IC50: 1.4 μM (MIF)[1] Ki: 0.96 μM (MIF)[1]

References

[1]. Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.

 Chemical & Physical Properties

Molecular Formula C18H13ClFN5O2
Molecular Weight 385.78
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