Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

(-)-Syringaresinol 4-O-β-D-glucopyranoside

Episyringaresinol 4'-O-β-D-glncopyranoside (compound 22), isolated from Alhagi sparsifolia Shap, is a natural potential neuroinflammatory inhibitor[1].

  • CAS Number: 137038-13-2
  • MF: C28H36O13
  • MW: 580.578
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 778.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 424.6±32.9 °C

TAS1553

TAS1553 is a potent, orally active protein–protein interaction (PPI) inhibitor with an IC50 values of 0.0396 μM. TAS1553 inhibits DNA replication and reduces intracellular dATP pool. TAS1553 induces apoptosis. TAS1553 can be used for cancer research[1].

  • CAS Number: 2166023-31-8
  • MF: C20H20ClFN4O5S
  • MW: 482.91
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Methyl-D-phenylalanine

H-D-Phe(4-Me)-OH is a phenylalanine derivative[1].

  • CAS Number: 49759-61-7
  • MF: C10H13NO2
  • MW: 179.216
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 323.5±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 149.5±24.6 °C

19-Hydroxy-10-deacetylbaccatin III

19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively[1].

  • CAS Number: 154083-99-5
  • MF: C29H36O11
  • MW: 560.59
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[PDP(polyethylene glycol)-2000] (aMMoniuM salt)

DSPE-PEG-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nepsilon-tetradecanoyl-L-lysine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nε-tetradecanoyl-L-lysine is a lysine derivative[1].

  • CAS Number: 1128181-23-6
  • MF: C35H50N2O5
  • MW: 578.782
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 780.6±60.0 °C at 760 mmHg
  • Melting Point: 140 °C
  • Flash Point: 425.9±32.9 °C

Amino(3-thienyl)acetic acid

(R)-2-Amino-2-(thiophen-3-yl)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1194-86-1
  • MF: C6H7NO2S
  • MW: 157.190
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 383.8±22.0 °C at 760 mmHg
  • Melting Point: 218℃
  • Flash Point: 185.9±22.3 °C

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 920519-32-0
  • MF: C30H36N2O8
  • MW: 552.61500
  • Catalog: Others
  • Density: 1.240±0.06 g/cm3 (20 °C, 760 mmHg)
  • Boiling Point: 753.3±60.0 °C (760 mmHg)
  • Melting Point: N/A
  • Flash Point: N/A

NLS PKKKRKV

NLS (PKKKRKV) is a peptide derived from the simian virus 40 large tumor antigen (SV40 large T antigen), as a method to enhance nuclear entry in the field of gene transfer research[1][2].

  • CAS Number: 95088-49-6
  • MF: C40H78N14O8
  • MW: 883.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BAY-069

BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer[1].

  • CAS Number: 2639638-66-5
  • MF: C22H14ClF3N2O3
  • MW: 446.81
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotinyl-pTH (1-34) (human) trifluoroacetate salt

Biotinyl-pTH (1-34) (human) is abiotinylated Teriparatide (HY-P0059).

  • CAS Number: 213779-14-7
  • MF: C181H291N55O51S2
  • MW: 4117.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Paneolilludinic acid

Paneolilludinic acid is a compound isolated from an endolichenic fungus Cryptomarasmius aucubae. Paneolilludinic acid significantly inhibits nitric oxide (NO) production[1].

  • CAS Number: 847586-20-3
  • MF: C15H22O3
  • MW: 250.33
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-CARBOXY-9-ACRIDANONE

Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1].

  • CAS Number: 24782-64-7
  • MF: C14H9NO3
  • MW: 239.22600
  • Catalog: Others
  • Density: 1.397g/cm3
  • Boiling Point: 469.9ºC at 760 mmHg
  • Melting Point: >185 °C(dec.)
  • Flash Point: 238ºC

Squalane-d62

Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].

  • CAS Number: 16514-83-3
  • MF: C30D62
  • MW: 485.195
  • Catalog: Cancer
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 470.3±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 217.8±0.0 °C

thiamphenicol

Thiamphenicol glycinate, an alpha-amino acid ester, is a prodrug of Thiamphenicol (HY-B0479)[1].

  • CAS Number: 2393-92-2
  • MF: C14H18Cl2N2O6S
  • MW: 413.27400
  • Catalog: Others
  • Density: 1.468g/cm3
  • Boiling Point: 672.5ºC at 760mmHg
  • Melting Point: 163-166ºC
  • Flash Point: 360.5ºC

Anticancer agent 170

Anticancer agent 170 (compound 3a) is a ketone derivative, and shows potency anti-cancer activity against A549, with the IC50 of 6.62 μM[1].

  • CAS Number: 24126-98-5
  • MF: C16H16O5
  • MW: 288.29500
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N,N-bis(2-hydroxyethyl)glycine

Bicine is a useful buffer in the range of physiological interest. Bicine is a derivative of the simple amino acid glycine[1].

  • CAS Number: 150-25-4
  • MF: C6H13NO4
  • MW: 163.17
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 388.5±27.0 °C at 760 mmHg
  • Melting Point: 190 °C (dec.)(lit.)
  • Flash Point: 188.8±23.7 °C

DOPE

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].

  • CAS Number: 4004-05-1
  • MF: C41H78NO8P
  • MW: 744.034
  • Catalog: Inflammation/Immunology
  • Density: 1.008g/cm3
  • Boiling Point: 759.2±70.0 °C at 760 mmHg
  • Melting Point: 200 °C
  • Flash Point: 413.0±35.7 °C

Iodobenzene-d5

Iodobenzene-d5 is the deuterium labeled 1-Iodobenzene[1].

  • CAS Number: 7379-67-1
  • MF: C6D5I
  • MW: 209.03900
  • Catalog: Others
  • Density: 1.868 g/mL at 25ºC
  • Boiling Point: 188ºC(lit.)
  • Melting Point: -29ºC(lit.)
  • Flash Point: 74ºC

BODIPY FL L-Cystine

BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm)[1][2].

  • CAS Number: 1180490-57-6
  • MF: C34H38B2F4N6O6S2
  • MW: 788.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Aminomethyl)phosphonic acid-d2

(Aminomethyl)phosphonic acid-d2 is the deuterium labeled (Aminomethyl)phosphonic acid[1].

  • CAS Number: 30926-24-0
  • MF: CH4D2NO3P
  • MW: 113.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Asp(OtBu)-OH-13C4,15N

Fmoc-Asp(OtBu)-OH-13C4,15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].

  • CAS Number: 1160760-08-6
  • MF: C1913C4H2515NO6
  • MW: 416.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3β-Hydroxytaraxast-20-en-16-one

3β-Hydroxytaraxast-20-en-16-one is a natural product isolated from eucalyptol/alcohol extract[1].

  • CAS Number: 42482-69-9
  • MF: C30H48O2
  • MW: 440.70092
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-Orn(N3)-OH (CHA)

Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group.

  • CAS Number: 1858224-18-6
  • MF: C16H31N5O4
  • MW: 357.45
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydrocortisone Valerate

Hydrocortisone 17-valerate (Cortisol 17-valerate) is a thiazolidine compound[1].

  • CAS Number: 57524-89-7
  • MF: C26H38O6
  • MW: 446.57600
  • Catalog: Others
  • Density: 1.21g/cm3
  • Boiling Point: 595.1ºC at 760mmHg
  • Melting Point: 217-220 °C
  • Flash Point: 195ºC

Human enteropeptidase-IN-3

Human enteropeptidase-IN-3 is an enteropeptidase inhibitor. Human enteropeptidase-IN-3 exhibits enteropeptidase activity and long duration of inhibitory state. Human enteropeptidase-IN-3 can be used for intetinal digestive related diseases research[1].

  • CAS Number: 1958037-36-9
  • MF: C22H22N4O8
  • MW: 470.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GSPT1 degrader-2

GSPT1 degrader-2 is a potent GSPT1 degrader[1].

  • CAS Number: 2803879-60-7
  • MF: C22H20ClN3O5
  • MW: 441.86
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glycosolone

Glycosoloneis a alkaloidthat can be found in Glycosmis pentaphylla[1].

  • CAS Number: 67879-81-6
  • MF: C16H19NO3
  • MW: 273.33
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 410.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.9±28.7 °C

Tabituximab

Tabituximab (OTSA101) is a humanized monoclonal antibody against frizzled class receptor 10 (FZD10)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trimethylgallic acid methyl ester

Methyl 3,4,5-trimethoxybenzoate can be synthesized from Gallic acid. Methyl 3,4,5-trimethoxybenzoate is mainly used in the production of Trimethoprim (TMP), Sulfa synergistic intermediates, and many other agents.

  • CAS Number: 1916-07-0
  • MF: C11H14O5
  • MW: 226.226
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 274.5±0.0 °C at 760 mmHg
  • Melting Point: 82-84 °C(lit.)
  • Flash Point: 115.2±18.2 °C