Squalane-d62

Modify Date: 2024-01-06 13:08:01

Squalane-d62 Structure
Squalane-d62 structure
Common Name Squalane-d62
CAS Number 16514-83-3 Molecular Weight 485.195
Density 0.8±0.1 g/cm3 Boiling Point 470.3±0.0 °C at 760 mmHg
Molecular Formula C30D62 Melting Point N/A
MSDS N/A Flash Point 217.8±0.0 °C

 Use of Squalane-d62


Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].

 Names

Name 2,6,10,15,19,23-hexamethyltetracosane-d62
Synonym More Synonyms

 Squalane-d62 Biological Activity

Description Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Kim SK, et al. Biological importance and applications of squalene and squalane. Adv Food Nutr Res. 2012;65:223-33.  

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 470.3±0.0 °C at 760 mmHg
Molecular Formula C30D62
Molecular Weight 485.195
Flash Point 217.8±0.0 °C
Exact Mass 484.874298
LogP 15.59
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.448

 Synonyms

Tetracosane-1,1,1,2,3,3,4,4,5,5,6,7,7,8,8,9,9,10,11,11,12,12,13,13,14,14,15,16,16,17,17,18,18,19,20,20,21,21,22,22,23,24,24,24-d, 2,6,10,15,19,23-hexa(methyl-d)-
dohexacontadeuterio-squalane
SQAFLFQPQRF-NH2
2,6,10,15,19,23-Hexakis[(H)methyl](H)tetracosane
2H,6H,10H,15H,19H,23H-dotriacontadeuterio-2,6,10,15,19,23-hexakis-trideuteriomethyl-tetracosane
H-SER-GLN-ALA-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2