Squalane

Modify Date: 2025-08-21 15:55:01

Squalane structure	Common Name	Squalane
	CAS Number	111-01-3	Molecular Weight	422.813
	Density	0.8±0.1 g/cm3	Boiling Point	470.3±0.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₆₂	Melting Point	−38 °C(lit.)
	MSDS	Chinese USA	Flash Point	217.8±0.0 °C

Use of Squalane

Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1].

Name	2,6,10,15,19,23-hexamethyltetracosane
Synonym	More Synonyms

Description	Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Squalane exhibits a huge potential in nutraceutical and pharmaceutical industries. Squalane shows anticancer, antioxidant, drug carrier, detoxifier, skin hydrating, and emollient activities have been reported both in animal models and in vitro environments[1].
References	[1]. Kim SK, et al. Biological importance and applications of squalene and squalane. Adv Food Nutr Res. 2012;65:223-33.

Density	0.8±0.1 g/cm3
Boiling Point	470.3±0.0 °C at 760 mmHg
Melting Point	−38 °C(lit.)
Molecular Formula	C₃₀H₆₂
Molecular Weight	422.813
Flash Point	217.8±0.0 °C
Exact Mass	422.485138
LogP	15.59
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.448
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

Squalane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XB6070000

CHEMICAL NAME :: Tetracosane, 2,6,10,15,19,23-hexamethyl-

CAS REGISTRY NUMBER :: 111-01-3

BEILSTEIN REFERENCE NO. :: 0776019

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C30-H62

MOLECULAR WEIGHT :: 422.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84063 No. of Facilities: 109 (estimated) No. of Industries: 3 No. of Occupations: 10 No. of Employees: 20918 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84063 No. of Facilities: 1980 (estimated) No. of Industries: 11 No. of Occupations: 32 No. of Employees: 149812 (estimated) No. of Female Employees: 126648 (estimated)

Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XB6070000
HS Code	2901100000

Precursor 10
CAS#:18794-84-8 (E)-β-Farnesene CAS#:111-02-4 Squalene CAS#:51627-57-7 6-azido-tetrazo... CAS#:78791-60-3 2,6,10,15,19,23...
CAS#:19317-11-4 FARNESAL CAS#:13786-84-0 3,7,11-trimethy... CAS#:78791-59-0 ((7,11-dimethyl... CAS#:3796-70-1 Geranylacetone
CAS#:59905-15-6 3-hydroxy-3,7,1... CAS#:106-28-5 (2E,6E)-Farnesol
DownStream 2
CAS#:2216-33-3 3-Methyloctane CAS#:79054-29-8 squalane cation

HS Code	2901100000
Summary	2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Biological importance and applications of squalene and squalane.

Adv. Food Nutr. Res. 65 , 223-33, (2012)

Squalene is a polyunsaturated hydrocarbon with a formula of C₃₀H₅₀. Squalene can be found in certain fish oils, especially shark liver oil, in high amounts and some vegetable oils in relatively smalle...

How membrane permeation is affected by donor delivery solvent.

Phys. Chem. Chem. Phys. 14(44) , 15525-38, (2012)

We investigate theoretically and experimentally how the rate and extent of membrane permeation is affected by switching the donor delivery solvent from water to squalane for different permeants and me...

Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model.

J. Oleo Sci. 62(1) , 21-8, (2013)

Active oxygen has been implicated in the pathogenesis of Parkinson's disease (PD); therefore, antioxidants have attracted attention as a potential way to prevent this disease. Squalene, a natural trit...

Squalane

Robane

Cosbiol

Perhydrosqualene

2,6,10,15,19,23-hexamethylteracosane

Spinacane

2,6,10,15,19,23-Hexamethyltetracosane

Dodecahydrosqualene

2,6,10,15,19,23-Hexamethyltetracosane,Cosbiol,Perhydrosqualene

Vitabiosol

MFCD00008953

Hexamethyltetracosane

EINECS 203-825-6

Tetracosane, 2,6,10,15,19,23-hexamethyl-

poly(ethylenepropylene)

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China
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