Squalene

Modify Date: 2024-01-01 22:56:44

Squalene structure	Common Name	Squalene
	CAS Number	111-02-4	Molecular Weight	410.718
	Density	0.8±0.1 g/cm3	Boiling Point	429.3±0.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₅₀	Melting Point	−75 °C(lit.)
	MSDS	Chinese USA	Flash Point	254.1±22.2 °C
	Symbol	GHS08	Signal Word	Danger

Use of Squalene

Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity.

Name	squalene
Synonym	More Synonyms

Description	Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity.
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Infection Natural Products >> Terpenoids and Glycosides
Target	Human Endogenous Metabolite
References	[1]. Muzalevskaya EN, et al. SQUALENE: PHYSIOLOGICAL AND PHARMACOLOGICAL PROPERTIES. Eksp Klin Farmakol. 2015;78(6):30-6.

Density	0.8±0.1 g/cm3
Boiling Point	429.3±0.0 °C at 760 mmHg
Melting Point	−75 °C(lit.)
Molecular Formula	C₃₀H₅₀
Molecular Weight	410.718
Flash Point	254.1±22.2 °C
Exact Mass	410.391266
LogP	13.09
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.492
Storage condition	2-8°C
Water Solubility	<0.1 g/100 mL at 19 ºC

Squalene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XB6010000

CHEMICAL NAME :: 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (all-E)-

CAS REGISTRY NUMBER :: 111-02-4

LAST UPDATED :: 199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 76,1021,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 76,1021,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9556 No. of Facilities: 20 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 737 (estimated) No. of Female Employees: 717 (estimated)

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H304
Precautionary Statements	P301 + P310-P331
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	F
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	XB6010000
Packaging Group	II; III
Hazard Class	4.1
HS Code	29012980

Precursor 9
CAS#:1299297-72-5 [(6E,10E,14E,18... CAS#:14050-42-1 2,3-Oxidosqualene CAS#:24163-93-7 (E,E)-3,7,11-tr... CAS#:6784-45-8 farnesyl chloride
CAS#:106-28-5 (2E,6E)-Farnesol CAS#:68690-45-9 (2E,6E)-3,7,11-... CAS#:502-67-0 (2E,6E)-3,7,11-... CAS#:56881-53-9 (E,E)-farnesyl ...
CAS#:6138-90-5 Geranyl bromide
DownStream 10
CAS#:3641-51-8 (R)-(+)-Methyls... CAS#:61898-58-6 menth-1-ene CAS#:3796-70-1 Geranylacetone CAS#:110-93-0 6-Methylhept-5-...
CAS#:67858-78-0 (4E,8E)-5,9,13-... CAS#:56882-09-8 (4E,8E,12E)-4,9... CAS#:928-68-7 2-Heptanone, 6-... CAS#:513-35-9 2-Methylbut-2-ene
CAS#:123-76-2 Levulinic acid CAS#:1073-91-2 ACETONEPEROXIDES

HS Code	2901299090
Summary	2901299090 unsaturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

The mannoprotein TIR3 (CAGL0C03872g) is required for sterol uptake in Candida glabrata.

Biochim. Biophys. Acta 1851(2) , 141-51, (2015)

Sterol uptake in the pathogenic fungus, Candida glabrata, occurs via the sterol transporter, CgAus1p. Azole inhibition of sterol biosynthesis can under certain circumstances be reversed by adding exog...

Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream.

Eur. J. Pharm. Biopharm. 88(3) , 614-24, (2015)

A novel adapalene-loaded solid lipid microparticle (SLMA) dispersion as a topical drug delivery system (TDDS) for follicular penetration has been introduced. The objective of the present study was to ...

Identification of a novel hypocholesterolemic protein, major royal jelly protein 1, derived from royal jelly.

PLoS ONE 9(8) , e105073, (2014)

Royal jelly (RJ) intake lowers serum cholesterol levels in animals and humans, but the active component in RJ that lowers serum cholesterol level and its molecular mechanism are unclear. In this study...

Squalene, all-trans-

(6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene

(E,E,E,E)-Squalene

2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene

(all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene

Squalene

triacontahexaene

Spinacen

EINECS 203-826-1

Supraene

MFCD00008912

2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (6E,10E,14E,18E)-

SQUALENE OIL

SPINACENE

SQUALENE WITH GC

(6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene

Squalen

2,6,10,15,19,23-Hexamethyltetracosa-(2E,6E,10E,14E,18E,22E)-2,6,10,14,18,22-hexaene

trans-Spinacene

BioBioPha
China
Product Name: Squalene
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Squalene
Price: ￥198.0/20mg ￥308.0/100ml ￥108.0/25ml
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Spinacene
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: Squalene
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Squalene suppliers

Price: ￥550/10 mM * 1 mL in DMSO

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Squalene

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