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111-02-4

111-02-4 structure
111-02-4 structure
  • Name: Squalene
  • Chemical Name: squalene
  • CAS Number: 111-02-4
  • Molecular Formula: C30H50
  • Molecular Weight: 410.718
  • Catalog: Natural product Moss
  • Create Date: 2019-01-07 00:16:51
  • Modify Date: 2024-01-01 22:56:44
  • Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity.

Name squalene
Synonyms Squalene, all-trans-
(6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene
(E,E,E,E)-Squalene
2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene
(all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene
Squalene
triacontahexaene
Spinacen
EINECS 203-826-1
Supraene
MFCD00008912
2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (6E,10E,14E,18E)-
SQUALENE OIL
SPINACENE
SQUALENE WITH GC
(6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene
Squalen
2,6,10,15,19,23-Hexamethyltetracosa-(2E,6E,10E,14E,18E,22E)-2,6,10,14,18,22-hexaene
trans-Spinacene
Description Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Muzalevskaya EN, et al. SQUALENE: PHYSIOLOGICAL AND PHARMACOLOGICAL PROPERTIES. Eksp Klin Farmakol. 2015;78(6):30-6.

Density 0.8±0.1 g/cm3
Boiling Point 429.3±0.0 °C at 760 mmHg
Melting Point −75 °C(lit.)
Molecular Formula C30H50
Molecular Weight 410.718
Flash Point 254.1±22.2 °C
Exact Mass 410.391266
LogP 13.09
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.492
Storage condition 2-8°C
Water Solubility <0.1 g/100 mL at 19 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XB6010000
CHEMICAL NAME :
2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (all-E)-
CAS REGISTRY NUMBER :
111-02-4
LAST UPDATED :
199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 76,1021,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 76,1021,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9556 No. of Facilities: 20 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 737 (estimated) No. of Female Employees: 717 (estimated)
Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H304
Precautionary Statements P301 + P310-P331
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes F
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS XB6010000
Packaging Group II; III
Hazard Class 4.1
HS Code 29012980
HS Code 2901299090
Summary 2901299090 unsaturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%