Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

eudesmol

Eudesmol is a sesquiterpenoid compound produced by Streptomyces tendae[1].

  • CAS Number: 51317-08-9
  • MF: C15H28O
  • MW: 224.382
  • Catalog: Neurological Disease
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 298.0±8.0 °C at 760 mmHg
  • Melting Point: 81-83ºC
  • Flash Point: 124.9±10.9 °C

Syringetin

Syringetin, a flavonoid derivative, is associated with increased BMP-2 production. Syringetin stimulates osteoblast differentiation at various stages, from maturation to terminally differentiated osteoblasts[1].

  • CAS Number: 4423-37-4
  • MF: C17H14O8
  • MW: 346.29
  • Catalog: Metabolic Disease
  • Density: 1.591 g/cm3
  • Boiling Point: 622.4ºC at 760mmHg
  • Melting Point: 287-289ºC
  • Flash Point: 1.591ºC

Carmoisine

Carmoisine (Azorubine) is an azo dye that can be used as a food additive[1][2].

  • CAS Number: 3567-69-9
  • MF: C20H12N2Na2O7S2
  • MW: 502.428
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300ºC
  • Flash Point: >225℃

1-(9,9,10,10,10-2H5)Decanol

1-Decanol-d5 is the deuterium labeled 1-Decanol[1].

  • CAS Number: 57368-00-0
  • MF: C10H17D5O
  • MW: 163.312
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 227.8±3.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 101.7±4.6 °C

H-Glu(Phe-OH)-OH

γ-Glu-Phe is a γ-3 glutamyl dipeptide found in sourdough.

  • CAS Number: 7432-24-8
  • MF: C14H18N2O5
  • MW: 294.30300
  • Catalog: Peptides
  • Density: 1.332g/cm3
  • Boiling Point: 622ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 330ºC

Angustanoic acid G

Angustanoic acid G is a natural product, that can be isolated from the roots of Illicium jiadifengpi[1].

  • CAS Number: 211814-30-1
  • MF: C19H24O3
  • MW: 300.39
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY-TS

BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols[1]. Ex: 490 nM; Em: 515 nM.

  • CAS Number: 1808174-52-8
  • MF: C20H21BF2N2O2S2
  • MW: 434.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Octadecyl-1H-indole-5-carboxylic acid

2-Octadecyl-1H-indole-5-carboxylic acid is a novel hypocholesterolaemic drug.

  • CAS Number: 81364-78-5
  • MF:
  • MW: 413.64
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Potassium carbonate-13C

Potassium carbonate-13C is the 13C labeled Potassium carbonate[1].

  • CAS Number: 122570-45-0
  • MF: CK2O3
  • MW: 139.19800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 891ºC(lit.)
  • Flash Point: N/A

5-Hydroxy-2-methylpyridine-d6

5-Hydroxy-2-methylpyridine-d6 is the deuterium labeled 5-Hydroxy-2-methylpyridine[1].

  • CAS Number: 2645412-74-2
  • MF: C6HD6NO
  • MW: 115.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,6-Bis[(2H3)methyl](2H6)naphthalene

2,6-Dimethylnaphthalene-d12 is the deuterium labeled 2,6-Dimethylnaphthalene[1].

  • CAS Number: 350820-12-1
  • MF: C12D12
  • MW: 168.298
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 264.4±10.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 110.5±9.7 °C

17:0-20:3 PI-d5 ammonium

17:0-20:3 PI-d5 (ammonium) is deuterium labeled 17:0-20:3 PI (ammonium).

  • CAS Number: 2342575-37-3
  • MF: C46H81D5NO13P
  • MW: 897.18
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-β-homo-Glu(OBzl)-OH

Boc-β-HoGlu(OBzl)-OH is a glutamic acid derivative[1].

  • CAS Number: 218943-30-7
  • MF: C18H25NO6
  • MW: 351.394
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 530.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 274.4±28.7 °C

Substance P(1-4)

Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation[1].

  • CAS Number: 57468-16-3
  • MF: C22H40N8O5
  • MW: 496.60400
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jolkinol A

Jolkinol A is a natural product that can be found in Euphorbia pubescens. Jolkinol A inhibits cell growth with GI50s of 95.3, 57.3, >100 µM for MCF-7, NCI-460, SF-268 cells, respectively[1].

  • CAS Number: 62820-11-5
  • MF: C29H36O6
  • MW: 480.592
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 643.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.1±25.0 °C

GB-1a

(-)-GB-1a is a potent antioxidant agent with an IC50 value of 148 µM[1].

  • CAS Number: 220611-41-6
  • MF: C30H22O10
  • MW: 542.49
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 895.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 301.8±27.8 °C

Littorine

Littorine is a alkaloid that can be isolated from Anthocercis fittorea and Datura species[1].

  • CAS Number: 21956-47-8
  • MF: C17H23NO3
  • MW: 289.36900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

trimethyl-[3-[4-[(3-methyl-1,3-benzothiazol-2-ylidene)methyl]quinolin-1-ium-1-yl]propyl]azanium,diiodide

TO-PRO 1 is a DNA binding fluorochrome, that atached to the surface of the Feraheme (FH) nanoparticle (NP), to obtain a fluorochrome-functionalized NP. TO-PRO 1 binds DNA through intercalation, and acts as a vital fluorochrome for necrotic cells[1].

  • CAS Number: 157199-59-2
  • MF: C24H29I2N3S
  • MW: 645.38100
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-16-diaminohexane

Fmoc-1,6-diaminohexane is an analog of Osw-1 which can be used to treat Alzheimer's disease and cancer, extracted from patent US 20140135279 A1.

  • CAS Number: 166410-37-3
  • MF: C21H26N2O2
  • MW: 338.44
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Methoxyanofinic acid

2-Methoxyanofinic acid is an iridoid compound that can be found in Gentiana macrophylla[1].

  • CAS Number: 179457-70-6
  • MF: C13H14O4
  • MW: 234.25
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 376.8±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 143.4±21.4 °C

Naringenin trimethyl ether

Naringenin trimethyl ether is a constituent of twigs and leaves of Aglaia duperreana. Naringenin trimethyl exhibits significant molluscicidal activity, with a LC50 of 3.9 μg/ mL for P. canaliculata[1].

  • CAS Number: 38302-15-7
  • MF: C18H18O5
  • MW: 314.332
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 500.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 222.1±30.2 °C

Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2 trifluoroacetate salt

Mca-PLA-Nva-Dap(Dnp)-AR-NH2 is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) [1].

  • CAS Number: 256394-92-0
  • MF: C48H66N14O15
  • MW: 1079.12000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

14,15-beta-dihydroxyklaineanone

14,15 D-dihydroxyklaineanone, a quassinoid isolated from the root of Eurycoma longifolia, possesses anti-cancer activity[1].

  • CAS Number: 137359-82-1
  • MF: C20H28O8
  • MW: 396.43200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HSR6071

HSR6071 is an antiallergic agent with potential for the treatment of asthma.

  • CAS Number: 111374-21-1
  • MF: C10H12N8O
  • MW: 260.25500
  • Catalog: Inflammation/Immunology
  • Density: 1.555g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TUG-1375

TUG-1375 is an agonist of free fatty acid receptor 2 (FFA2/GPR43), with a pKi of 6.69. TUG-1375 is inactive on FFA3, FFA4, PPARα, PPARγ, PPARδ, LXRα or LXRβ[1].

  • CAS Number: 2247372-59-2
  • MF: C22H19ClN2O4S
  • MW: 442.92
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Columbianetin

Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity[1][2].

  • CAS Number: 3804-70-4
  • MF: C14H14O4
  • MW: 246.259
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 443.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 171.9±22.2 °C

PF-02575799

PF-02575799 is a microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 0.77±0.29 nM.

  • CAS Number: 863491-70-7
  • MF: C42H37FN4O4
  • MW: 680.76600
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Prolactin-Releasing Peptide (12-31), bovine

Prolactin-Releasing Peptide (12-31), bovine is a peptide fragment of prolactin-releasing peptide (PrRP). PrRP is RF-amide peptides expressed in brain areas involved inpain modulation. Prolactin-Releasing Peptide (12-31), bovine can be used for the research of nervous system disease[1].

  • CAS Number: 209466-90-0
  • MF: C44H80N14O15
  • MW: 2242.54
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

hexasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulphonato-4-[(4-sulphonatophenyl)azo]phenyl]azo]naphthalene-2-sulphonate]

Direct Red 80 (Sirius Red) is a polyazo dye used principally in staining methods for collagen and amyloid. Direct Red 80 does not release benzidine upon degradation and is safer than many traditional direct dyes[1].

  • CAS Number: 2610-10-8
  • MF: C45H26N10Na6O21S6
  • MW: 1373.07000
  • Catalog: Others
  • Density: 1.85 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N,N-dimethyl-N-((phenyl-d5)methyl)tetradecan-1-aminium bromide

N,N-dimethyl-N-((phenyl-dd5)methyl)tetradecan-1-aminium bromide is the deuterium labeled N,N-dimethyl-N-((phenyl-d5)methyl)tetradecan-1-aminium bromide[1].

  • CAS Number: 1515861-68-3
  • MF: C23H42BrN
  • MW: 412.49028
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A