TUG-1375

Modify Date: 2024-01-10 22:54:41

TUG-1375 structure	Common Name	TUG-1375
	CAS Number	2247372-59-2	Molecular Weight	442.92
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₉ClN₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TUG-1375

TUG-1375 is an agonist of free fatty acid receptor 2 (FFA2/GPR43), with a pKi of 6.69. TUG-1375 is inactive on FFA3, FFA4, PPARα, PPARγ, PPARδ, LXRα or LXRβ[1].

Name	TUG-1375

Description	TUG-1375 is an agonist of free fatty acid receptor 2 (FFA2/GPR43), with a pKi of 6.69. TUG-1375 is inactive on FFA3, FFA4, PPARα, PPARγ, PPARδ, LXRα or LXRβ[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	pKi: 6.69 (FFA2)[1]
In Vitro	TUG-1375 exhibits pEC50 of 7.11 in the cAMP FFA2 assay, also active on murine FFA2 orthologue (pEC50, 6.44 ± 0.13 in the cAMP assay)[1].
References	[1]. Hansen AH, et al. Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties. J Med Chem. 2018 Nov 8;61(21):9534-9550.

Molecular Formula	C₂₂H₁₉ClN₂O₄S
Molecular Weight	442.92
Storage condition	2-8℃

DC Chemicals Limited
China
Product Name: TUG-1375
Price: $850.0/100mg $1500.0/250mg $3000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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