Substance P(1-4)
Modify Date: 2024-01-02 21:05:40
Substance P(1-4) structure
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Common Name | Substance P(1-4) | ||
|---|---|---|---|---|
| CAS Number | 57468-16-3 | Molecular Weight | 496.60400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H40N8O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Substance P(1-4)Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation[1]. |
| Name | 1-[6-amino-2-[[1-[2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Substance P(1-4) (0.1 nM-1 μM) inhibits endogenous erythroid colony (EEC) formation in PV bone marrow cultures[1]. Substance P(1-4) (0.1 nM-1 μM; CD36+/GpA- cells) decreases of erythroid colony numbers of 47% and inhibits proliferation of PV CD36+/GpA- cells of 30 %[1]. Cell Viability Assay[1] Cell Line: PV CD36+/GpA- cells Concentration: 0.1 nM-1 μM Incubation Time: 2 days Result: Inhibited proliferation of PV CD36+/GpA- cells of 30 %. Apoptosis Analysis[1] Cell Line: PV CD36+/GpA- cells Concentration: 10 nM Incubation Time: 2 days Result: Increased the percentage of cell death of 27.3%. |
| Molecular Formula | C22H40N8O5 |
|---|---|
| Molecular Weight | 496.60400 |
| Exact Mass | 496.31200 |
| PSA | 220.96000 |
| LogP | 1.11560 |
| Arg-Pro-Lys-Pro |
| 1-(6-amino-2-{[1-(2-amino-5-carbamimidamidopentanoyl)pyrrolidin-2-yl]formamido}hexanoyl)pyrrolidine-2-carboxylic acid |
| substance P(1-4) |
| SUBSTANCE P,Fragment 1-4 |
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Substance P (1-4)
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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