Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Propan-2-amine-d6 hydrochloride

Propan-2-amine-d6 (hydrochloride) is the deuterium labeled H-Lys-OH.2HCl[1].

  • CAS Number: 126794-59-0
  • MF: C3H4D6ClN
  • MW: 101.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Phe-Ala-OH

(tert-Butoxycarbonyl)-L-phenylalanyl-L-alanine is an alanine derivative[1].

  • CAS Number: 55677-48-0
  • MF: C17H24N2O5
  • MW: 336.38300
  • Catalog: Others
  • Density: 1.182g/cm3
  • Boiling Point: 587.8ºC at 760mmHg
  • Melting Point: 90-93℃
  • Flash Point: 309.3ºC

6-Oxochelerythrine

Oxychelerythrine is an alkaloid that can be isolated from Zanthoxylum integrifoliolum. Oxychelerythrine exhibits cytotoxicity against P-388 and HT-29 cell lines with ED50s of 3.25 and 5.48 μg/mL, respectively[1].

  • CAS Number: 28342-33-8
  • MF: C21H17NO5
  • MW: 363.36
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 615.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 326.1±31.5 °C

Fmoc-D-Cha-OH

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclohexylpropanoic acid is an alanine derivative[1].

  • CAS Number: 144701-25-7
  • MF: C24H27NO4
  • MW: 393.475
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 610.5±38.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 323.0±26.8 °C

1,2,15,16-tetrahydrotanshiquinone

Trijuganone B (Tetrahydro tanshinone I) can be extracted from from the roots of Salvia miltiorrhiza f. alba. Trijuganone B inhibits the proliferation of leukemia cells[1][2].

  • CAS Number: 126979-84-8
  • MF: C18H16O3
  • MW: 280.31800
  • Catalog: Cancer
  • Density: 1.29g/cm3
  • Boiling Point: 470ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 210.2ºC

Abiraterone metabolite 1

Abiraterone metabolite 1 is a 5β-reduced metabolite of abiraterone. Abiraterone, a steroidal drug, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer.

  • CAS Number: 1940176-03-3
  • MF: C24H33NO
  • MW: 351.52
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Chlormethiazole hydrochloride

Clomethiazole hydrochloride is a sedative and anticonvulsant. Clomethiazole hydrochloride is neuroprotective and prevents the degeneration of serotonergic nerve terminals induced by 3,4-methylenedioxymethamphetamine (MDMA)[1][2].

  • CAS Number: 6001-74-7
  • MF: C6H9Cl2NS
  • MW: 297.52200
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 136 °C
  • Flash Point: N/A

N,N-dimethyl-4-(phenyldiazenyl)aniline-d5

N,N-dimethyl-4-(phenyldiazenyl)aniline-d5 is the deuterium labeled N,N-dimethyl-4-(phenyldiazenyl)aniline[1].

  • CAS Number: 1398109-08-4
  • MF: C14H10D5N3
  • MW: 230.320
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 371.0±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 178.2±23.2 °C

Transcainide

Transcainide (R 54718) is an orally active antiarrhythmic agent[1].

  • CAS Number: 88296-62-2
  • MF: C22H35N3O2
  • MW: 373.53200
  • Catalog: Cardiovascular Disease
  • Density: 1.13g/cm3
  • Boiling Point: 529.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 274ºC

Trifluoperazine N-β-D-Glucuronide

Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1].

  • CAS Number: 165602-90-4
  • MF: C27H32F3N3O6S
  • MW: 583.62000
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CPI-613

CPI-613 is a lipoic acid analog that inhibits pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts mitochondrial metabolism and shows strong antitumor activity.

  • CAS Number: 95809-78-2
  • MF: C22H28O2S2
  • MW: 388.586
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 553.0±50.0 °C at 760 mmHg
  • Melting Point: 63-65℃
  • Flash Point: 288.3±30.1 °C

4-Feruloylquinic acid

4-Feruloylquinic acid may be a potential biomarker for food products[1].

  • CAS Number: 2613-86-7
  • MF: C17H20O9
  • MW: 368.335
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 656.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 238.9±25.0 °C

N-ForMyl-D-leucine, tech.

(R)-2-formamido-4-methylpentanoic acid is a leucine derivative[1].

  • CAS Number: 44978-39-4
  • MF: C7H13NO3
  • MW: 159.18300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 132-136℃
  • Flash Point: N/A

METHYL 2-(1-AMINOCYCLOPROPYL)ACETATE HYDROCHLORIDE

Methyl 2-amino-2-cyclopropylacetate hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 535936-86-8
  • MF: C6H12ClNO2
  • MW: 165.618
  • Catalog: Others
  • Density: 1.147g/cm3
  • Boiling Point: 162ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 36ºC

Tyrosinase (192-200) (human, mouse) acetate salt

Tyrosinase (192-200), human mouse is a nonapeptide. Tyrosinase (192-200), human mouse can be recognized by cytolytic T cell (CTL) on the HLA-B44 molecule. Tyrosinase (192-200), human mouse can be used in research of melanoma associated cancers[1].

  • CAS Number: 170294-35-6
  • MF: C54H77N13O17
  • MW: 1180.266
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

680C91

680C91 is an orally active, selective tryptophan 2,3-dioxygenase (TDO) inhibitor with a Ki of 51 nM. TDO is the key enzyme of tryptophan catabolism. 680C91 can be used for the research of cancer immunotherapy and Alzheimer’s Disease[1][2][3][4].

  • CAS Number: 163239-22-3
  • MF: C15H11FN2
  • MW: 238.26000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PhIP

PhIP is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat[1][2]. DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity[2].

  • CAS Number: 105650-23-5
  • MF: C13H12N4
  • MW: 224.26100
  • Catalog: Cancer
  • Density: 1.3 g/cm3
  • Boiling Point: 468.9ºC at 760 mmHg
  • Melting Point: 300ºC
  • Flash Point: 237.4ºC

D-Mannose isomerase

D-Mannose isomerase is a carbohydrate isomerase catalyzing the reversible isomerization of d-mannose to d-fructose. D-Mannose isomerase belongs to the N-acylglucosamine 2-epimerase (AGE) superfamily along with AGE, cellobiose 2-epimerase (CE), and aldose-ketose isomerase (AKI)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jasminoside B

Jasminoside B is a natural compound isolated from the rhizomes of Asarum sieboldii with immunosuppressive activity[1].

  • CAS Number: 214125-04-9
  • MF: C16H26O8
  • MW: 346.373
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 580.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.1±23.6 °C

Sephadex G 200

Sephadex G 200 is a hydrophilic gel that can be used as a gel filter filler (Particle size range: 40-120 μm; Sphere protein separation range: 5k-600k Da)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Beacon (47-73)

Beacon (47-73) is a C-terminal peptide fragment 47-73 of Beacon, and Beacon is a protein of 73 amino acid. Beacon (47-73) can be used for metabolic syndrome research[1][2].

  • CAS Number: 681153-68-4
  • MF: C156H217N35O46S
  • MW: 3350.66
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

STM2120

STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM[1].

  • CAS Number: 2762286-04-2
  • MF: C18H15N5O2
  • MW: 333.34
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

p-Dimethylaminobenzaldehyde

p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles[1].

  • CAS Number: 100-10-7
  • MF: C9H11NO
  • MW: 149.190
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 176-177 ºC (17 mmHg)
  • Melting Point: 72-75 °C(lit.)
  • Flash Point: 164 ºC

Diosbulbin B

Diosbulbin B is a diterpene lactone isolated from D. bulbifera L., with anti-tumor activity. Diosbulbin B can induce liver injury[1][2].

  • CAS Number: 20086-06-0
  • MF: C19H20O6
  • MW: 344.358
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 574.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 301.4±30.1 °C

Sterigmatocystine

Sterigmatocystine, a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor, has developmental, teratogenic, and carcinogenic effects in animals[1][2][3].

  • CAS Number: 10048-13-2
  • MF: C18H12O6
  • MW: 324.284
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 569.7±50.0 °C at 760 mmHg
  • Melting Point: 246ºC with decomp
  • Flash Point: 215.9±23.6 °C

gliquidone

Gliquidone (AR-DF 26) is an anti-diabetic drug in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.

  • CAS Number: 33342-05-1
  • MF: C27H33N3O6S
  • MW: 527.632
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 179ºC
  • Flash Point: N/A

Delphinidin 3-diglucoside

Delphinidin 3-diglucoside (Delphinidol 3-sophoroside) is a phenolic compound that can be isolated from Punica granatum[1].

  • CAS Number: 59212-40-7
  • MF: C27H31ClO17
  • MW: 662.98
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aluminum Glycinate

Aluminum Glycinate, an organo-metallic compound, is an antacid. Aluminum Glycinate can be used for the research of indigestion, acid reflux and ulcers[1].

  • CAS Number: 13682-92-3
  • MF: C2H3AlNO4
  • MW: 135.055
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Asparagine hydrate

(R)-2,4-diamino-4-oxobutanoic acid hydrate is an asparagine derivative[1].

  • CAS Number: 5794-24-1
  • MF: C4H10N2O4
  • MW: 150.133
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 408.5ºC at 760 mmHg
  • Melting Point: 275 °C (dec.)(lit.)
  • Flash Point: 200.9ºC

Neurogranin Fragment 28-43

Neurogranin 28-43 is a biological active peptide. (selective PKC substrate)

  • CAS Number: 146554-17-8
  • MF: C78H134N28O19S
  • MW: 1800.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A