p-Dimethylaminobenzaldehyde

Modify Date: 2025-08-20 11:39:56

p-Dimethylaminobenzaldehyde structure	Common Name	p-Dimethylaminobenzaldehyde
	CAS Number	100-10-7	Molecular Weight	149.190
	Density	1.1±0.1 g/cm3	Boiling Point	176-177 ºC (17 mmHg)
	Molecular Formula	C₉H₁₁NO	Melting Point	72-75 °C(lit.)
	MSDS	USA	Flash Point	164 ºC
	Symbol	GHS02, GHS05, GHS07	Signal Word	Danger

Use of p-Dimethylaminobenzaldehyde

p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles[1].

Name	4-Dimethylaminobenzaldehyde
Synonym	More Synonyms

Description	p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Axel Ehmann, et al. The van URK-Salkowski reagent — a sensitive and specific chromogenic reagent for silica gel thin-layer chromatographic detection and identification of indole derivatives. Journal of Chromatography A. Volume 132, Issue 2, 11 February 1977, Pages 267-276.

Density	1.1±0.1 g/cm3
Boiling Point	176-177 ºC (17 mmHg)
Melting Point	72-75 °C(lit.)
Molecular Formula	C₉H₁₁NO
Molecular Weight	149.190
Flash Point	164 ºC
Exact Mass	149.084061
PSA	20.31000
LogP	1.81
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.596
Storage condition	2-8°C
Stability	Stable, but light sensitive. Incompatible with bases, strong oxidizing agents.
Water Solubility	0.3 g/L (20 ºC)

p-Dimethylaminobenzaldehyde MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU5775000

CHEMICAL NAME :: Benzaldehyde, p-(dimethylamino)-

CAS REGISTRY NUMBER :: 100-10-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C9-H11-N-O

MOLECULAR WEIGHT :: 149.21

WISWESSER LINE NOTATION :: VHR DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HINEL* Hine Laboratories Reports. (San Francisco, CA) Volume(issue)/page/year: AF33(657)-11756,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1800 mg/kg/9D-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80179 No. of Facilities: 622 (estimated) No. of Industries: 8 No. of Occupations: 13 No. of Employees: 6871 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80179 No. of Facilities: 1897 (estimated) No. of Industries: 7 No. of Occupations: 20 No. of Employees: 23642 (estimated) No. of Female Employees: 15264 (estimated)

Symbol	GHS02, GHS05, GHS07
Signal Word	Danger
Hazard Statements	H226-H290-H314-H332-H335
Precautionary Statements	P210-P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R52/53
Safety Phrases	S7-S16-S24/25-S26-S61-S45-S39-S36/37/39
RIDADR	UN 2920 8/PG 2
WGK Germany	1
RTECS	CU5775000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2912210000

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DownStream 10
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HS Code	2922399090
Summary	2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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N,N-Dimethyl-p-aminobenzaldehyde

p-(N,N-Dimethylamino)benzaldehyde

p-N,N-Dimethylaminobenzaldehyde

Ehrlichs

p-dimethylaminobenzaldehyde

EINECS 202-819-0

EHRICH'S REAGENT

N,N-Dimethyl-4-aminobenzaldehyde

Para-Dimethylaminobenzaldehyde

p-Formyldimethylaniline

4-(Dimethylamino)benzaldehyde

HYDRAZINE-REAGENT

4-N,N-dimethylaminobenzaldehyde

MFCD00003381

p-DAB

Benzaldehyde, 4-(dimethylamino)-

reagensehrlichovo

EHRLICH'S REAGENT

ERLICH'S REAGENT

VHR DN1&1

p-(Dimethylamino)benzaldehyde

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p-Dimethylaminobenzaldehyde

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