Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

DHX9-IN-3

DHX9-IN-3 (Compound 621) is an ATP-dependent inhibitor of RNA helicase A (DHX9) with potential for cancer research[1].

  • CAS Number: 2973401-57-7
  • MF: C24H20ClFN4O4S2
  • MW: 547.02
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TMB-PS

TMB-PS(102062-36-2) is N-(3-sulfopropyl)-3,3',5,5'-tetramenthylbenzidine sodium salt; White - pale yellow crystalline powder, soluble in water, can be used under neutral, acidic and alkaline conditions.

  • CAS Number: 102062-36-2
  • MF: C19H26N2O3S
  • MW: 362.486
  • Catalog: Dye Reagents
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 230-240ºC
  • Flash Point: N/A

Eflornithine

Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

  • CAS Number: 70052-12-9
  • MF: C6H12F2N2O2
  • MW: 182.16800
  • Catalog: Others
  • Density: 1.293g/cm3
  • Boiling Point: 347ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 163.7ºC

AC-PHE-OET

(S)-Ethyl 2-acetamido-3-phenylpropanoate is a phenylalanine derivative[1].

  • CAS Number: 2361-96-8
  • MF: C13H17NO3
  • MW: 235.27900
  • Catalog: Others
  • Density: 1.096g/cm3
  • Boiling Point: 402.1ºC at 760mmHg
  • Melting Point: 92 °C
  • Flash Point: 197ºC

Boc-N-ethylglycine

Boc-N-Ethylglycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 149794-10-5
  • MF: C9H17NO4
  • MW: 203.236
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 302.7±21.0 °C at 760 mmHg
  • Melting Point: 87-88℃
  • Flash Point: 136.9±22.1 °C

Zika virus-IN-1

Zika virus-IN-1 (Compd 2) is a Zika virus inhibitor, with an EC50 of 1.56 μM [1].

  • CAS Number: 2527912-80-5
  • MF: C30H37N3O3Si
  • MW: 515.72
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

IRGRILHDGAYSLTLQGLGIH

IRGRILHDGAYSLTLQGLGIH is a multi-epitope class II rat HER2/neu peptide. IRGRILHDGAYSLTLQGLGIH can be used for the research class II HER2-DC1 vaccine studies[1].

  • CAS Number: 1443436-79-0
  • MF: C102H168N32O28
  • MW: 2290.62
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Pro-Pro-Pro-Pro-OH

Tetraproline is a fragment sequence in tristetraprolin (TTP). Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements[1].

  • CAS Number: 21866-90-0
  • MF: C20H30N4O5
  • MW: 406.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 729.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 395.2±32.9 °C

Cyanine 3 Tyramide

Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids[1][2].

  • CAS Number: 174961-75-2
  • MF: C39H47N3O8S2
  • MW: 749.94
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Arg-OMe.2HCL

H-Arg-OMe.2HCL is an arginine derivative[1].

  • CAS Number: 26340-89-6
  • MF: C7H18Cl2N4O2
  • MW: 261.149
  • Catalog: Others
  • Density: 1.31g/cm3
  • Boiling Point: 329.9ºC at 760 mmHg
  • Melting Point: ~190 °C (dec.)
  • Flash Point: 153.3ºC

D,L-erythro-PDMP hydrochloride

D,L-erythro-PDMP hydrochloride is an erythro isomer of PDMP. D,L-erythro-PDMP hydrochloride causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase[1][2].

  • CAS Number: 80943-40-4
  • MF: C23H39ClN2O3
  • MW: 427.02
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nafocare B1

Nafocare B1 is a synthetic immune biological response modifier.

  • CAS Number: 93135-89-8
  • MF: C11H12O7
  • MW: 256.20900
  • Catalog: Inflammation/Immunology
  • Density: 1.72g/cm3
  • Boiling Point: 332.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 154.9ºC

Guanosine 2',3'-Cyclic Phosphate Triethylamine Salt

2′,3′-cGMP triethylamine (Guanosine 2',3'-cyclic phosphate triethylamine) is an active compound. 2′,3′-cGMP triethylamine can be used for various studies[1].

  • CAS Number: 73647-09-3
  • MF: C16H27N6O7P
  • MW: 446.39500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glutinol acetate

Glutinyl acetate is a triterpene that can be extracted from Dorstenia arifolia. Triterpenes are reported to exhibit anti-inflammatory, antimicrobial, antiviral, cytotoxic and cardiovascular effects[1].

  • CAS Number: 6426-44-4
  • MF: C32H52O2
  • MW: 468.75
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 505.1±29.0 °C at 760 mmHg
  • Melting Point: 192℃ (methanol )
  • Flash Point: 256.2±11.8 °C

Curcumin β-D-Glucuronide

Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer[1][2].

  • CAS Number: 227466-72-0
  • MF: C27H28O12
  • MW: 544.50400
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Uncargenin C

Uncargenin C is a triterpenoid, which can be isolated from Uncaria rhychophyllo Miq. Jacks. The intermediate of Uncargenin C has anti-leukemia activity, but not itself[1][2].

  • CAS Number: 152243-70-4
  • MF: C30H48O5
  • MW: 488.70
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 621.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 343.7±28.0 °C

H-D-Glu-OBzl

H-D-Glu-OBzl is a glutamic acid derivative[1].

  • CAS Number: 79338-14-0
  • MF: C12H15NO4
  • MW: 237.252
  • Catalog: Others
  • Density: 1.245g/cm3
  • Boiling Point: 416.0±40.0 °C at 760 mmHg
  • Melting Point: 154ºC
  • Flash Point: 205.4±27.3 °C

Magnoloside A

Magnoloside A (compound 4) is a main phenylethanoid glycoside in Houpo. Magnoloside A can be used in the research of functional dyspepsia (FD)[1].

  • CAS Number: 113557-95-2
  • MF: C29H36O15
  • MW: 624.59
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 908.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 294.7±27.8 °C

Liquiritigenin-7-O-beta-D-glucopyranosyl-(1-->2)-beta-D-apiofuranoside

Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside (Liquiritigenin-7-apiosylglucoside) is a flavonoid isolated from the roots of Glycyrrhiza, has weaker cytotoxicity against several tumor cells and normal cells[1].

  • CAS Number: 135432-48-3
  • MF: C26H30O13
  • MW: 550.51
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Leu-Gly-βNA

H-Leu-Gly-βNA can be used as a substrate to detect the presence or absence of N-acetyl-BD-galactosaminidase[1].

  • CAS Number: 100930-00-5
  • MF: C18H23N3O2
  • MW: 313.39
  • Catalog: Metabolic Disease
  • Density: 1.177g/cm3
  • Boiling Point: 605ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 319.7ºC

PK14105

PK14105 is a biological evaluation as a potential radioligand for PET studies of PBBS receptors.in vivo binding experiments, in which PK 14105 was injected into rats with unilaterallylesioned striata, demonstrate that PK 14105 rapidly crosses the blood-brain-barrier and that thereis a marked retention of radioactivity in the lesioned striatum not seen in the unlesioned striatum or cerebellar vermis[1]It can also inhibit receptor ligands, calcium channel ligands and co-transporter in all salivary glands. [2]

  • CAS Number: 107257-28-3
  • MF: C21H20FN3O3
  • MW: 381.40000
  • Catalog: Others
  • Density: 1.257g/cm3
  • Boiling Point: 555.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 289.9ºC

1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone-d3

1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone-d3 is the deuterium labeled 1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone[1].

  • CAS Number: 1396967-82-0
  • MF: C18H23D3O
  • MW: 261.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-His-Met-OH

Histidylmethionine is a biologically active peptide.

  • CAS Number: 2488-11-1
  • MF: C11H18N4O3S
  • MW: 286.35100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N3-Cystamine-Suc-OSu

N3-Cystamine-Suc-OSu is a click chemistry reagent containing an azide group. N3-Cystamine-Suc-OSu can be used for the research of various biochemical[1].

  • CAS Number: 1987341-40-1
  • MF: C12H17N5O5S2
  • MW: 375.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Pro-Val-OH

H-Pro-Val-OH is a deprotonation dipeptide containing proline, which can catalyze the Michael addition reaction of acetone to trans-β-nitrostyrene. H-Pro Val OH can also serve as a substrate for fibroblast enzymes and prolinase, and has potential applications in biochemical analysis[1][2][3][4].

  • CAS Number: 52899-09-9
  • MF: C10H18N2O3
  • MW: 214.26
  • Catalog: Others
  • Density: 1.15g/cm3
  • Boiling Point: 451.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 226.6ºC

Colestyramine

Colestyramine (Cholestyramine) is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol.

  • CAS Number: 11041-12-6
  • MF: C21H30ClN
  • MW: 331.923
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

KSDSC

KSDSC is a penta-peptide, correlated positively with hairpin DNA with tetramer loops. Therefore, KSDSC joins hands with hairpin DNA (hpDNA) with improved selectivity as sensing materials in the detection system, used for surface plasmon resonance imaging (SPRi)[1].

  • CAS Number: 2439064-83-0
  • MF: C19H34N6O10S
  • MW: 538.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

chloroacetyl-dl-phenylalanine

N-Chloroacetyl-DL-phenylalanine is a phenylalanine derivative[1].

  • CAS Number: 7765-11-9
  • MF: C11H12ClNO3
  • MW: 241.67100
  • Catalog: Others
  • Density: 1.312g/cm3
  • Boiling Point: 482.2ºC at 760mmHg
  • Melting Point: 127 °C
  • Flash Point: 245.4ºC

Bocconoline

Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD)[1].

  • CAS Number: 1322007-90-8
  • MF: C22H21NO5
  • MW: 379.41
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

blumeatin b

Blumeatin B is a flavonoid and an antioxidant agent[1].

  • CAS Number: 79995-67-8
  • MF: C17H16O7
  • MW: 332.30
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 627.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 234.4±25.0 °C