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1322007-90-8

1322007-90-8 structure
1322007-90-8 structure
  • Name: Bocconoline
  • Chemical Name: Bocconoline
  • CAS Number: 1322007-90-8
  • Molecular Formula: C22H21NO5
  • Molecular Weight: 379.41
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2022-11-21 11:50:06
  • Modify Date: 2024-03-03 13:41:15
  • Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD)[1].

Name Bocconoline
Description Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD)[1].
Related Catalog
Target

EEA1[1]

In Vitro Bocconoline (compound 3) (30 μM; 24 h; hONS cells) affects primarily on EEA1 marker intensity in the cytoplasm, mitochondria marker intensity in inner region of the cytoplasm and microtubule-associated protein light chain 3B (LC3b) marker intensity in inner region of cytoplasm[1].
References

[1]. Nguyen DT, et al. Chemical constituents from Macleaya cordata (Willd) R. Br. and their phenotypic functions against a Parkinson's disease patient-derived cell line. Bioorg Med Chem. 2020 Nov 1;28(21):115732.

Molecular Formula C22H21NO5
Molecular Weight 379.41