Curcumin β-D-Glucuronide
Modify Date: 2024-01-02 14:18:05
Curcumin β-D-Glucuronide structure
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Common Name | Curcumin β-D-Glucuronide | ||
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| CAS Number | 227466-72-0 | Molecular Weight | 544.50400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Curcumin β-D-GlucuronideCurcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer[1][2]. |
| Name | (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]-2-methoxyphenoxy]oxane-2-carboxylic acid |
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| Synonym | More Synonyms |
| Description | Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer[1][2]. |
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| Related Catalog | |
| In Vivo | Curcumin-β-D-glucuronide (90 mg/kg; i.p. thrice a week for 3 weeks) exhibit potent anti-tumor effects on KRASm/TP53w HCT116 xenograft model[1]. Animal Model: Female BALB/c/AnNCr j‐nu/nude mice (6 weeks) were transplanted KRASm/TP53w HCT116 cells[1] Dosage: 90 mg/kg Administration: I.p. thrice a week for 3 weeks Result: Suppressed tumor growth by 38%. Did not show a negative impact on body weight. Attenuated NF‐κB activity. |
| References |
| Molecular Formula | C27H28O12 |
|---|---|
| Molecular Weight | 544.50400 |
| Exact Mass | 544.15800 |
| PSA | 189.28000 |
| LogP | 0.93530 |
| 4-[(1E,6E)-7-(4-Hydroxy-3-methoxyphenyl)-3,5-dioxo-1,6-heptadien-1-yl]-2-methoxyphenyl |A-D-Glucopyranosiduronic Acid |
| Curcumin |A-D-Glucuronide |