Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

4α-Methylcholesterol

4α-Methylcholesterol is a Cholesterol derivative. 4α-Methylcholesterol can oxidize 3-hydroxy steroid, with the apparent Km of 12.6 μM[1][2].

  • CAS Number: 15073-00-4
  • MF: C28H48O
  • MW: 400.68
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(9E,12Z)-9,12-Tetradecadien-1-ol 1-acetate

(9Z,12E)-Tetradecadien-1-yl acetate is the main component of pheromone of insects Ephestia Kuehniella and Plodia Interpunctella, and cereal pests[1].

  • CAS Number: 31654-77-0
  • MF: C16H28O2
  • MW: 252.39200
  • Catalog: Others
  • Density: 0.89g/cm3
  • Boiling Point: 334.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 102.3ºC

N-Tetradecanoyl-DL-homoserine lactone

N-Tetradecanoyl-DL-homoserine lactone is a serine derivative[1].

  • CAS Number: 98206-80-5
  • MF: C18H33NO3
  • MW: 311.46000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SynB1

SynB1 is a cell penetrating polypeptide, internalized by, or is associated with lipid vesicle (LV). SynB1 can be used to lipid vesicle-mediated delivery to cells[1].

  • CAS Number: 1207092-86-1
  • MF: C89H151N37O27
  • MW: 2171.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Iriflophenone 3-C-beta-D-glucopyranoside

Iriflophenone 3-C-β-D-glucopyranoside, isolated from Cyclopia genistoides, has antioxidant activity[1].

  • CAS Number: 104669-02-5
  • MF: C19H20O10
  • MW: 408.356
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 669.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 239.9±25.0 °C

PXS-5153A

PXS-5153A is a potent, selective, orally active and fast-acting inhibitor of lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3), with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.

  • CAS Number: 2125956-82-1
  • MF: C20H25Cl2FN4O2S
  • MW: 475.41
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glaucogenin C Mono-D-thevetoside

Glaucogenin C mono-D-thevetoside can be isolated from the roots of Cynanchum stauntonii[1].

  • CAS Number: 849201-84-9
  • MF: C28H40O9
  • MW: 520.61
  • Catalog: Others
  • Density: 1.3±0.0 g/cm3
  • Boiling Point: 717.1±0.0 °C at 760 mmHg
  • Melting Point: 185-187℃
  • Flash Point: 236.1±0.0 °C

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one (Compound 2) is a pyranone isolated from the hexane extract of the aerial parts of Hypericum choisianum[1].

  • CAS Number: 1153624-36-2
  • MF: C16H14O3
  • MW: 254.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sabinene

Sabinene is a perfume additive which is being explored as the component for the next generation aircraft fuel.

  • CAS Number: 3387-41-5
  • MF: C10H16
  • MW: 136.234
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 164.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 36.7±0.0 °C

a-TGF (34-43), rat

a-TGF (34-43), rat is an active peptide. a-TGF (34-43), rat can be used in the research of immunity[1].

  • CAS Number: 95596-38-6
  • MF: C44H69N15O13S2
  • MW: 1080.24
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3,4,5,6-Pentachlorobiphenyl-2′,3′,4′,5′,6′-d5

2,3,4,5,6-Pentachlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 2,3,4,5,6-Pentachlorobiphenyl-2′,3′,4′,5′,6′[1].

  • CAS Number: 1219798-92-1
  • MF: C12D5Cl5
  • MW: 331.46
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Thiohydantoin

2-Thiohydantoin acts as an inhibitor for the corrosion of mild steel in 0.1 M HCl and its inhibition efficiency is both concentration and immersion time dependent[1].

  • CAS Number: 503-87-7
  • MF: C3H4N2OS
  • MW: 116.142
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 229-231 °C (dec.)(lit.)
  • Flash Point: N/A

Tetramethylbenzidine

3,3’,5,5’-Tetramethylbenzidine(TMB) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).

  • CAS Number: 54827-17-7
  • MF: C16H20N2
  • MW: 240.343
  • Catalog: Dye Reagents
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 368.6±37.0 °C at 760 mmHg
  • Melting Point: 168-171 °C(lit.)
  • Flash Point: 210.8±26.0 °C

Inclacumab

Inclacumab (Anti-Human selectin P Recombinant Antibody) is a humanized monoclonal IgG4 antibody selectively targets P-selectin with a Kd value of 9.9 nM. Inclacumab inhibits P-selectin glycoprotein ligand 1 (PSGL-1) mimetic peptide bind with P-selectin with an IC50 value of 1.9 µg/mL and strongly inhibits cell adhesion[1][2][3].

  • CAS Number: 1256258-86-2
  • MF:
  • MW:
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Poricoic acid H

Poricoic acid H is a triterpene[1].

  • CAS Number: 415724-85-5
  • MF: C31H48O5
  • MW: 500.71
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Deruxtecan-d2

Deruxtecan-d2 is the deuterium labeled Potassium oleate[1].

  • CAS Number: 2760715-87-3
  • MF: C52H54D2FN9O13
  • MW: 1036.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Hydroxy-4-methoxybenzaldehyde-d3

Isovanillin-d3 is the deuterium labeled Isovanillin[1]. Isovanillin is an aldehyde oxidase inhibitor[2]. Antispasmodic activities[3]. Antidiarrheal activities[4].

  • CAS Number: 74495-73-1
  • MF: C8H8O3
  • MW: 152.14700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Lys-Asp-OH

H-Lys-Asp-OH is a biologically active peptide.

  • CAS Number: 20556-18-7
  • MF: C10H19N3O5
  • MW: 261.27500
  • Catalog: Others
  • Density: 1.326 g/cm3
  • Boiling Point: 541.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 281.1ºC

Calcium L-aspartate

Aspartic acid calcium (Calcium L-aspartate) is a chelate where calcium is attached to an amino acid naming L-Aspartic acid. L-Aspartic acid is an amino acid and serves as a building block for proteins in the body.

  • CAS Number: 21059-46-1
  • MF: C4H5CaNO4
  • MW: 171.165
  • Catalog: Cardiovascular Disease
  • Density: 1.514g/cm3
  • Boiling Point: 264.1ºC at 760 mmHg
  • Melting Point: 270-271ºC
  • Flash Point: 113.5ºC

SW203668

SW203668 is a benzothiazole compound, shows anti-tumor activity against lung cancer cell lines (IC50=0.022-0.116 μM)[1].

  • CAS Number: 1673556-40-5
  • MF: C22H19N3O2S
  • MW: 389.470
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Grisnilimab

Grisnilimab (WT1), a IgG2a monoclonal antibody anti-CD7, is a tumor suppressor involved in the etiology of Wilms' tumor. Grisnilimab regulates the transcription of multiple target genes and may participate in the post-transcriptional processing of RNA[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Analgesic agent-1

Analgesic agent-1, a potent analgesic agent, shows significant analgesic effect.

  • CAS Number: 2230243-92-0
  • MF: C23H19FN4OS
  • MW: 418.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Maximin 9

Maximin 9 is an antimicrobial peptide derived from toad Bombina maxima[1].

  • CAS Number: 853262-58-5
  • MF: C137H218N40O33S
  • MW: 2985.51
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CP-319340(free base)

CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.

  • CAS Number: 186390-35-2
  • MF: C27H23F3N4O
  • MW: 476.49
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lesabelimab

Lesabelimab (LDP) is an immunoglobulin G1-kappa anti-CD274 monoclonal antibody. CD274 is an immune checkpoint ligand, represses antitumour immunity through the interaction with PDCD1 receptor[1][2].

  • CAS Number: 2475402-56-1
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

threoninium dihydrogen phosphate

O-Phospho-L-threonine is a threonine derivative[1].

  • CAS Number: 1114-81-4
  • MF: C4H10NO6P
  • MW: 199.09900
  • Catalog: Others
  • Density: 1.671g/cm3
  • Boiling Point: 454ºC at 760mmHg
  • Melting Point: 169 °C
  • Flash Point: 228.4ºC

Sudan I

Sudan I is an organic compound, typically classified as an azo dye.

  • CAS Number: 842-07-9
  • MF: C16H12N2O
  • MW: 248.279
  • Catalog: Dye Reagents
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 443.7±28.0 °C at 760 mmHg
  • Melting Point: 131-133 °C
  • Flash Point: 290.2±13.3 °C

Banksialactone A

Banksialactone A is the metabolite of an Australian fungus, Aspergillus banksianus[1].

  • CAS Number: 1135775-06-2
  • MF: C13H16O6
  • MW: 268.263
  • Catalog: Infection
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 544.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 211.2±23.6 °C
  • CAS Number: 307322-32-3
  • MF: C14H12N4O
  • MW: 252.271
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Transcriptional Intermediary Factor 2 (TIF2) (740-753)

Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a TIF-2 coactivator peptide composed of 14 amino acids and covers the residue range 740-753 of TIF-2 protein[1].

  • CAS Number: 359821-54-8
  • MF: C75H124N20O25
  • MW: 1705.91
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A