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54827-17-7

54827-17-7 structure
54827-17-7 structure
  • Name: Tetramethylbenzidine
  • Chemical Name: Tetramethylbenzidine
  • CAS Number: 54827-17-7
  • Molecular Formula: C16H20N2
  • Molecular Weight: 240.343
  • Catalog: Chemical reagent Organic reagent Aromatic hydrocarbon
  • Create Date: 2018-12-15 05:23:33
  • Modify Date: 2025-08-20 20:11:47
  • 3,3’,5,5’-Tetramethylbenzidine(TMB) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).
Name Tetramethylbenzidine
Synonyms 3355TMB
3,3,5',5'-Tetramethylbenzidine
UNII-3B3T5CB8EO
TMB/H
TMB-E
TMB/M
3,3’,5,5’-tetramethylbenzidine
EINECS 259-364-6
TMB
BM BLUE
3,3',5,5'-Tetramethyl-4,4'-biphenyldiamine
3,3',5,5'-tetramethyl-4,4'-diamino-1,1'-biphenyl
TMB QUICK
3,3',5,5'-tetramethylbenzidine
Tmbz
MFCD00007748
3,3',5,5'-Tetramethylbiphenyl-4,4'-diamine
3,5,3',5'-tetramethylbenzidine
TMB EASY
TMB-B
[1,1'-Biphenyl]-4,4'-diamine, 3,3',5,5'-tetramethyl-
Description 3,3’,5,5’-Tetramethylbenzidine(TMB) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).
Related Catalog
Density 1.1±0.1 g/cm3
Boiling Point 368.6±37.0 °C at 760 mmHg
Melting Point 168-171 °C(lit.)
Molecular Formula C16H20N2
Molecular Weight 240.343
Flash Point 210.8±26.0 °C
Exact Mass 240.162643
PSA 52.04000
LogP 3.40
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.618
Storage condition 2-8°C
Stability Stable, but moisture sensitive and may be light sensitive. Incompatible with water, strong oxidizing agents.
Water Solubility Slightly soluble.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DV2300000
CHEMICAL NAME :
(1,1'-Biphenyl)-4,4-diamine, 3,3',5,5'-tetramethyl-
CAS REGISTRY NUMBER :
54827-17-7
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C16-H20-N2
MOLECULAR WEIGHT :
240.38
WISWESSER LINE NOTATION :
ZR B1 F1 DR DZ C1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
135 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
30700 ug/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),37,1988
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S36/37
RIDADR UN 2796 8/PG 2
WGK Germany 3
RTECS DV2300000
Hazard Class 8.0
HS Code 29215990
HS Code 2921590090
Summary 2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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