186390-35-2

186390-35-2 structure

186390-35-2 structure

Name: CP-319340(free base)
Chemical Name: CP-319340(free base)
CAS Number: 186390-35-2
Molecular Formula: C₂₇H₂₃F₃N₄O
Molecular Weight: 476.49
Catalog: Research Areas Metabolic Disease
Create Date: 2018-03-19 14:09:34
Modify Date: 2024-01-03 11:20:06
CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.

Name	CP-319340(free base)

Description	CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	MTP[1][2]
In Vitro	Microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) are necessary for lipoprotein assembly. MTP binds to ApoB with high affinity involving ionic interactions. MTP interacts at multiple sites in the N-terminal beta alpha structural domain of apoB[3].
References	[1]. Sugi, Kiyoshi, et al. Process for producing 4-(2-methylphenyl)benzotrifluoride. EP1700837A1. [2]. Ye, Jin, et al. Treating hepatitis C virus infection. US20080175864A1. [3]. Hussain MM, et al. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J Lipid Res. 2003 Jan;44(1):22-32.

Molecular Formula	C₂₇H₂₃F₃N₄O
Molecular Weight	476.49