MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart.
Anatumomab mafenatox (ABR-214936) is a 73 KDa recombinant protein to recognize the tumor-associated antigen 5T4, which is widely expressing in malignancy. Anatumomab mafenatox is between a modified form of SEA and a murine Fab. The main side effects of Anatumomab mafenatox are reported to include fever, low blood pressure, pain, nausea and drowsiness[1].
α-Mannosidase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
SARM1-IN-2 is a SARM1 inhibitor extracted from patent WO2019236890A1 example 82. SARM1-IN-2 can be used for the research of axonal degeneration[1].
Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1); an antioxidant dietary supplement.IC50 value:Target: Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)?protein kinase C (PKC) pathway）of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect[1][2].
Sulforhodamine B acid chloride is a fluorescent protein label forming stable conjugates.
Cresyl violet acetate is a red fluorescent stain, which can be used to stain neurons.
H-Pro-Pro-Gln-OH is a oligopeptide with excellent dipeptidyl peptidase-IV (DPP-IV) inhibitory activity[1].
Ru(bpy)2(dcbpy)NHS (dihexafluorophosphate) combined with gold nanoparticle amplification can be used for the determination of lysozyme with electrochemiluminescence[1].
2,4-Dihydroxy-3-methoxyacetophenone is a chemical agent[1].
Human Papillomavirus (HPV) E7 protein (49-57) is the H-2d-restricted human papillomavirus (HPV) E749-57 epitope (short peptide spanning the 49th to 57th amino acid residues in the E7 protein)[1].
OfChi-h-IN-1 is a potent OfChi-h inhibitor with a Ki value of 0.33 μM. OfChi-h-IN-1 dramatically inhibit the growth and development of Ostrinia nubilalis larvae, and it shows higher insecticidal activity than Hexaflumuron (HY-B1848).?OfChi-h-IN-1 serves as novel candidates for insect growth regulator[1].
α-GLU stands for α-glucosidase. α-GLU hydrolyzes starch and disaccharides via targeting to terminal, non-reducing (1→4)-linked α-D-glucose residues to produce α-glucose. α-GLU is substrate selective[1].
Boc-Tyr(Bzl)-OH is a tyrosine derivative[1].
Cussosaponin C is a compound isolated from Pulsatilla koreana Nakai[1].
Acetylcholine iodide is a common neurotransmitter found in the central and peripheral nerve system[1].
Latinone, a neoflavonoid isolated from Dalbergia cochinchinensis, has antiosteoporotic activity[1].
8-Lavandulylkaempferol is a flavonoid that can be isolated from Sophora flaWescens. 8-Lavandulylkaempferol exhibits cytotoxic activity against the KB epidermoid carcinoma cell line with an IC50 of 15.1 μg/mL[1].
Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress[1][2].
Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis[1].
1,3,9-Trimethyluric acid is a natural alkaloid compound[1].
2,2-Dimethyl-1,3-dioxolane-4-methanol-d5 is the deuterium labeled 2,2-Dimethyl-1,3-dioxolane-4-methanol[1].
Mogroside III, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1].
7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant[1].
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC50s of 5.6 and 2.9 μg/mL respectively[1].
Detajmium (L-tartrate) is an antiarrhythmic compound. Detajmium has effect on V max in both dog ventricular muscle and Purkinje fibers was frequency dependent[1].
Fmoc-Pro-OH is a proline derivative[1].
Cholecystokinin is a peptide hormone. Cholecystokinin, as a hunger suppressant, inhibits food intake and stimulates the digestion of fat and protein. Cholecystokinin can be used for the research of gastrointestinal system[1][2][3].
Diglycolic acid-d4 is the deuterium labeled Diglycolic acid[1].