22457-89-2
22457-89-2 structure
- Name: Benfotiamine
- Chemical Name: benfotiamine
- CAS Number: 22457-89-2
- Molecular Formula: C19H23N4O6PS
- Molecular Weight: 466.448
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-05-18 08:00:00
- Modify Date: 2024-01-02 16:44:40
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Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1); an antioxidant dietary supplement.IC50 value:Target: Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)?protein kinase C (PKC) pathway）of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
| Name | benfotiamine |
|---|---|
| Synonyms |
berdi
S-benzoylthiamine monophosphate bietamine biotamin S-[(2Z)-2-{[(4-Amino-2-methyl-5-pyrimidinyl)methyl](formyl)amino}-5-(phosphonooxy)-2-penten-3-yl] benzenecarbothioate betivina S-Benzoyl-thiamin-monophosphat EINECS 245-013-4 Benfotiamine neurostop S-Benzoylthiamine O-Monophosphate 8088c.b. Benfotiaminum S-Benzoyl-thiamin-O-monophosphat S-benzoylthiamine-O-monophosphate MFCD00057343 MilgaMMa btmp benzenecarbothioic acid, S-[(1Z)-2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl] ester nitanevril tabiomyl |
| Description | Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1); an antioxidant dietary supplement.IC50 value:Target: Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)?protein kinase C (PKC) pathway）of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1. |
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| Related Catalog | |
| References |
[6]. Benfotiamine |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 745.1±70.0 °C at 760 mmHg |
| Melting Point | 165ºC |
| Molecular Formula | C19H23N4O6PS |
| Molecular Weight | 466.448 |
| Flash Point | 404.4±35.7 °C |
| Exact Mass | 466.107605 |
| PSA | 191.05000 |
| LogP | 1.81 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.645 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
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