Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Cyclo(-Gly-Arg-Gly-Glu-Ser-Pro) trifluoroacetate salt

Cyclo(Gly-Arg-Gly-Glu-Ser-Pro) (c(GRGESP)) is a peptide that serves as a control peptide for the inhibitory peptide cyclo-GRGDSP[1].

  • CAS Number: 2022956-43-8
  • MF: C23H37N9O9
  • MW: 583.6
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-TERT-BUTOXYCARBONYL-AZIDO-D-ALANINE

Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

  • CAS Number: 225780-77-8
  • MF: C8H14N4O4
  • MW: 230.22100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2'-Aminoacetophenone

2'-Aminoacetophenone is an aromatic compound containing a ketone substituted by one alkyl group, and a phenyl group. 2'-Aminoacetophenone can be used as a breath biomarker for the detection of Ps. Aeruginosa infections in the cystic fibrosis lung[1].

  • CAS Number: 551-93-9
  • MF: C8H9NO
  • MW: 135.163
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 251.8±13.0 °C at 760 mmHg
  • Melting Point: 20 °C
  • Flash Point: 106.1±19.8 °C

Fmoc-Abu-OH

Fmoc-Abu-OH is an alanine derivative[1].

  • CAS Number: 135112-27-5
  • MF: C19H19NO4
  • MW: 325.358
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 552.4±50.0 °C at 760 mmHg
  • Melting Point: 161 °C
  • Flash Point: 287.9±30.1 °C

GM1a Ganglioside oligosaccharide

GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses[1].

  • CAS Number: 67063-78-9
  • MF: C34H57N2O26·Na
  • MW: 955.8
  • Catalog: Inflammation/Immunology
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 1365.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 779.5±34.3 °C

(S)-Canocapavir

(S)-Canocapavir is the isomer of Canocapavir (HY-147255A). Canocapavir (ZM-H1505R) has orally antiviral activity. Canocapavir is a HBV capsid inhibitor that can be used in the research of Chronic hepatitis B[1].

  • CAS Number: 2137847-77-7
  • MF: C27H21BrFN5O3
  • MW: 562.39
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Apigenin-6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside

Apigenin-6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside is a flavonoid with antioxidant activity. Apigenin-6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside can be isolated from Traditional Chinese Medicine TiepiShihu[1].

  • CAS Number: 85700-46-5
  • MF: C25H26O13
  • MW: 534.47
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DT-2

DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG). DT-2 inhibits PKG catalyzed phosphorylation (Ki: 12.5 nM)[1].

  • CAS Number: 1220985-78-3
  • MF: C122H223N53O23
  • MW: 2800.42
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Triglochinic acid

Triglochinic acid is a monomeric compound isolated from tubers of Pinellia pedatisecta Schott[1].

  • CAS Number: 31795-12-7
  • MF: C7H8O6
  • MW: 188.13500
  • Catalog: Others
  • Density: 1.549±0.06 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Azido-D-alanine

3-Azido-D-alanine is an azido-modified D-alanine (HY-41700). 3-Azido-D-alanine can be used in the research of click chemistry labeling[1].

  • CAS Number: 105928-88-9
  • MF: C3H6N4O2
  • MW: 130.10534
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

O-Desmethyl mycophenolic acid methyl ester

O-Desmethyl mycophenolic acid methyl ester is an intermediate in the synthesis of Mycophenolic acid[1].

  • CAS Number: 33431-38-8
  • MF: C17H20O6
  • MW: 320.33700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NIH-12848

NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor with an IC50 of 1 μM.

  • CAS Number: 959551-10-1
  • MF: C20H14F3N3S
  • MW: 385.412
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

fmoc-l-4,4'-biphenylalanine

Fmoc-Bip(4,4')-OH is an alanine derivative[1].

  • CAS Number: 199110-64-0
  • MF: C30H25NO4
  • MW: 463.524
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 700.7±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 377.6±32.9 °C

Methyl acetylacetate-13C4

Methyl acetylacetate-13C4 is an isotopically labeled compound. Methyl acetylacetate-13C4 can be used for various biochemical studies[1].

  • CAS Number: 107694-17-7
  • MF: C13C4H8O3
  • MW: 120.09
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sculponeatin N

Sculponeatin N is a ent-kaurane diterpene derivative compound isolated from the plant Isodon sculponeata[1].

  • CAS Number: 1169805-98-4
  • MF: C25H40O4
  • MW: 404.583
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 515.0±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 166.1±16.7 °C

(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol

(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol is a cucurbitane-type triterpenoid. (19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol has been tested to no effect against 5 cancer cell lines, MCF-7, HepG2, Du145, Colon205 and HL-60 by MTT assay[1].

  • CAS Number: 1301267-02-6
  • MF: C32H52O4
  • MW: 500.75
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ampliflu Red

ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).

  • CAS Number: 119171-73-2
  • MF: C14H11NO4
  • MW: 257.241
  • Catalog: Dye Reagents
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 618.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 327.9±31.5 °C

Isobutylshikonin

Isobutylshikonin is a kind of shikonin pigments from hairy root culture of Lithospermum canescens[1].

  • CAS Number: 52438-12-7
  • MF: C20H22O6
  • MW: 358.385
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 565.2±45.0 °C at 760 mmHg
  • Melting Point: 88ºC
  • Flash Point: 295.6±28.7 °C

Boc-Phe(3-F)-OH

(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid is a phenylalanine derivative[1].

  • CAS Number: 114873-01-7
  • MF: C14H18FNO4
  • MW: 283.295
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 425.0±40.0 °C at 760 mmHg
  • Melting Point: 75-80 °C
  • Flash Point: 210.8±27.3 °C

sulfosuccinimidyl 6-((4-azido-2-nitrophenyl)amino)hexanoate

Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker[1].

  • CAS Number: 102568-43-4
  • MF: C16H18N6O9S
  • MW: 470.41
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ezutromid

Ezutromid is a novel Small utrophin's translation modulator with EC50 of 0.4 uM .In vitro: 1) SMT C1100 induces increased levels of utrophin RNA in human muscle cells.2) Treatment of human DMD cells with SMT C1100 lead to a 2-fold increase in utrophin protein levels at an optimal concentration of 0.3 uM after 3 days of treatment. 3) SMT C1100 wassafe and well tolerated with plasma concentrations achieved suf?cient to cause a 50% increase in concentrations of utrophin in cells. 4) SMT C1100 led to a 30% increase in Utrn mRNA level and resulted in a 2.0-fold increase in UTRN protein level .In vivo: 1)The reference for administration is 50 mg/kg. 2) it was considered that no toxicity was determined for SMT C1100 administered by oral gavage to the mouse up to dose levels of 2000 mg/kg/day for 28 days.Note: You can dissolve the products in phosphate buffered saline (PBS), 0.1% Tween-20, 5% DMSO)

  • CAS Number: 945531-77-1
  • MF: C19H15NO3S
  • MW: 337.39200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt

Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) is a biologically active peptide.

  • CAS Number: 2022956-56-3
  • MF: C143H240N42O45S
  • MW: 3299.8
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Murrangatin

Murrangatin is a coumarin that can be found in Murraya exotica[1].

  • CAS Number: 37126-91-3
  • MF: C15H16O5
  • MW: 276.284
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 500.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.5±23.6 °C

H-Lys(crotonyl)-OH

N6-(But-2-enoyl)-L-lysine is a lysine derivative[1].

  • CAS Number: 1338823-35-0
  • MF: C10H18N2O3
  • MW: 214.262
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 463.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 233.9±28.7 °C

Piperlactam S

Piperlactam S is an active compound. Piperlactam S can be isolated from Piper kadsura. Piperlactam S can be used for the research of chronic inflammation[1].

  • CAS Number: 188546-49-8
  • MF: C17H13NO4
  • MW: 295.29
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lalistat 2

Lalistat 2 is a specific inhibitor of lysosomal acid lipase (LAL) with no effect on other forms of lipase[1].

  • CAS Number: 1234569-09-5
  • MF: C13H20N4O2S
  • MW: 296.388
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 438.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 219.0±28.7 °C

PAR-2 (6-1) amide (mouse, rat) trifluoroacetate salt

LRGILS-NH2 is a reverse-sequence protease-activated receptor-2 (PAR-2)-inactive, negative control, and SLIGRL-NH2 is a PAR-2-activating peptide[1].

  • CAS Number: 245329-01-5
  • MF: C29H56N10O7
  • MW: 656.81800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-AMINO-4-PENTENOIC ACID HYDROCHLORIDE

2-Aminopent-4-enoic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 7685-44-1
  • MF: C5H9NO2
  • MW: 115.131
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 222.7±23.0 °C at 760 mmHg
  • Melting Point: 251-253ºC
  • Flash Point: 88.5±22.6 °C

H-Arg-4MβNA

H-Arg-4MβNA is a substrate for cathepsin H, used for the detection of enzyme activity in gel electrophoresis.

  • CAS Number: 60285-94-1
  • MF: C17H23N5O2
  • MW: 329.397
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GLP-2 (rat)

GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR)[1][2].

  • CAS Number: 195262-56-7
  • MF: C166H256N44O56S
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A