2'-Aminoacetophenone

Modify Date: 2024-01-02 15:40:24

2'-Aminoacetophenone Structure
2'-Aminoacetophenone structure
Common Name 2'-Aminoacetophenone
CAS Number 551-93-9 Molecular Weight 135.163
Density 1.1±0.1 g/cm3 Boiling Point 251.8±13.0 °C at 760 mmHg
Molecular Formula C8H9NO Melting Point 20 °C
MSDS Chinese USA Flash Point 106.1±19.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2'-Aminoacetophenone


2'-Aminoacetophenone is an aromatic compound containing a ketone substituted by one alkyl group, and a phenyl group. 2'-Aminoacetophenone can be used as a breath biomarker for the detection of Ps. Aeruginosa infections in the cystic fibrosis lung[1].

 Names

Name 2-Aminoacetophenone
Synonym More Synonyms

 2'-Aminoacetophenone Biological Activity

Description 2'-Aminoacetophenone is an aromatic compound containing a ketone substituted by one alkyl group, and a phenyl group. 2'-Aminoacetophenone can be used as a breath biomarker for the detection of Ps. Aeruginosa infections in the cystic fibrosis lung[1].
Related Catalog
References

[1]. Amy J Scott-Thomas , et al. 2-Aminoacetophenone as a Potential Breath Biomarker for Pseudomonas Aeruginosa in the Cystic Fibrosis Lung. BMC Pulm Med. 2010 Nov 7;10:56.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 251.8±13.0 °C at 760 mmHg
Melting Point 20 °C
Molecular Formula C8H9NO
Molecular Weight 135.163
Flash Point 106.1±19.8 °C
Exact Mass 135.068420
PSA 43.09000
LogP 1.62
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.571
Storage condition 0-6°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AM5775000
HS Code 2914399090

 Synthetic Route

 Customs

HS Code 2922399090
Summary 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles21

More Articles
Quantitative analysis of 2-aminoacetophenone in off-flavored wines by stable isotope dilution assay.

J. AOAC Int. 79(2) , 583-6, (1996)

Isotope dilution analysis was used to quantitate 2-aminoacetophenone in wines exhibiting the so-called untypical aging off-flavor. d3-Aminoacetophenone was synthesized and used as isotopomeric interna...

Glycosylation of aromatic amines III: Mechanistic implications of the pH-dependent glycosylation of various aromatic amines (kynurenine, 2'-aminoacetophenone, daptomycin, and sulfamethoxzaole).

J. Pharm. Sci. 98(12) , 4639-49, (2009)

Glycosylation reaction kinetics of a series of aromatic amines (kynurenine, 2'-aminoacetophenone, daptomycin, and sulfamethoxazole) was compared to propose a unifying reaction mechanism. Kinetic studi...

Purification and characterization of 2-aminoacetophenone reductase of newly isolated Burkholderia sp. YT.

J. Biosci. Bioeng. 104(5) , 416-9, (2007)

We found that a newly isolated Burkholderia sp. produced (R)-2-amino-1-phenylethanol from 2-aminoacetophenone, showing the high stereospecificity. NADPH-dependent 2-aminoacetophenone reductase purifie...

 Synonyms

2-amino acetophenone
EINECS 209-002-8
2-Acetylaniline
MFCD00007717
Ethanone, 1-(2-aminophenyl)-
2'-Amonioacetophenone
2'-AminoActophenone
1-(2-Aminophenyl)ethanone
o-Acetylaniline
FEMA 3906
o-Aminoacetophenone
2`-Aminoacetophenone
ortho-Aminoacetophenone
o-Aminoacetylbenzene
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