Tetanus Toxin (830–844) is a biological active peptide. (tetanus toxin-derived peptide TT830–844 CD4+ T-cell epitope. This promiscuous CD4+ T-cell epitope can bind to a wide range of HLA–DRB molecules and is thus expected to activate CD4+ T-cell responses in a large part of the human population)
2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change materials (PCMs). Amino-2-methyl-1,3-propanediol can be used to make surfactants, vulcanization accelerators and as a biological buffer[1].
Quercimeritrin, isolated from the leaves of Ixeridium dentatum, exhibits significant amylase activity[1].
Sephadex G75 is a Gel-filtration media. Sephadex G75 also is a dextran-based matrix and used for Gel-filtration chromatography[1].
Fmoc-D-Phe(2-Cl)-OH is a phenylalanine derivative[1].
Alisol B 23-acetate, a natural triterpenoid, produces protective effects against EE-induced cholestasis, due to FXR-mediated gene regulation.IC50 Value:Target: Anti-hepatotoxic natural product. In vitro: Alisol-B 23-acetate has an effect on FXR activation in a dose-dependent manner using luciferase reporter assay in HepG2 cells [3].In vivo: In alisol B 23-acetate-treated mice, the changes in transporters and enzymes, as well as ameliorative liver histology were abrogated by FXR antagonist guggulsterone [1]. Alisol B 23-acetate treatment in a dose-dependent manner resulted in protection against hepatotoxicity induced by CCl4via FXR activation. Through FXR activation, alisol B 23-acetate promoted hepatocyte proliferation via an induction in hepatic levels of FoxM1b, Cyclin D1 and Cyclin B1. Alisol B 23-acetate also reduced hepatic bile acids through a decrease in hepatic uptake transporter Ntcp, bile acid synthetic enzymes Cyp7a1, Cyp8b1, and an increase in efflux transporter Bsep, Mrp2 expression. In addition, alisol B 23-acetate induced the expression of STAT3 phosphorylation, and STAT3 target genes Bcl-xl and SOCS3, resulting in decreased hepatocyte apoptosis [2].
Nicosulfuron-d6 is the deuterium labeled Nicosulfuron[1]. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[2].
5-Methyl-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate-d3 is the deuterium labeled 5-Methyl-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate[1].
D-(+)-Talose-13C is the 13C labeled D-(+)-Talose[1].
Thymalfasin is an immunomodulating agent able to enhance the Thl immune response. Sequence: N-acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn.
19-iodo-5-cholesten-3beta-ol 3-acetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
1β-Hydroxy-2-oxopomolic acid is a compound isolated from methanolic extract of leaves of Eriobotrya deflexa[1].
Boc-L-Ala-OH-3-13C is a 13C-labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
Methoxyamine (O-Methylhydroxylamine) hydrochloride is a reagent in the preparation of O-methyl oximes or synthesis of O-methyl oximes from aldehydes[1].
(R)-2-((S)-2-amino-4-methylpentanamido)-4-methylpentanoic acid dihydrate is a leucine derivative[1].
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly
Yunnankadsurin B is a dibenzocyclooctene-type lignan isolated from the stems of Schisandra chinensis (Kadsura)[1].
Sodium carboxyl methylstarch is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm)[1].
15-Deoxoeucosterol is a compound isolated from the bulbs of Scilla scilloides[1].
Trityl olmesartan medoxomil impurity III is an impurity of Trityl olmesartan medoxomil. Trityl olmesartan medoxomil is an intermediate of Olmesartan medoxomil[1].
2,6-Di-O-methyl-β-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
H-D-Val-Leu-Lys-AFC (Plasmin substrate) is a biological active peptide. (This is a fluorescent plasmin substrate, Abs/Em=380/500 nm.Plasmin belongs to the family of serine proteases. It plays a key role in fibrinolysis by dissolving fibrin in blood clots. Besides fibrinolysis, plasmin is also involved in such physiological and pathological processes as wound healing, liver repair, and the maintenance of liver homeostasis.)
L-Proline-13C5,1-15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
Acetyl-PHF6QV amide is a biologically active peptide.
N-(3-Phenylpropionyl)glycine is a Glycine (HY-Y0966) derivative[1].
2-4-(2-Cyanoethyl)(2-phenylethyl)aminophenylazo-5-nitrobenzonitrile is a storage-stable, fluid, nonagglomerating dispersions of azo dye[1].
N3-PhAc-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].
N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester is a glutamic acid derivative[1].
Fmoc-Ile-OPfp is an isoleucine derivative[1].