Nicosulfuron-d6

Modify Date: 2024-01-14 21:16:47

Nicosulfuron-d6 Structure
Nicosulfuron-d6 structure
Common Name Nicosulfuron-d6
CAS Number 1189419-41-7 Molecular Weight 416.44200
Density N/A Boiling Point N/A
Molecular Formula C15H12D6N6O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nicosulfuron-d6


Nicosulfuron-d6 is the deuterium labeled Nicosulfuron[1]. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[2].

 Names

Name Nicosulfuron-d6
Synonym More Synonyms

 Nicosulfuron-d6 Biological Activity

Description Nicosulfuron-d6 is the deuterium labeled Nicosulfuron[1]. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Louis Carles, et al. Nicosulfuron Degradation by an Ascomycete Fungus Isolated From Submerged Alnus Leaf Litter. Front Microbiol. 2018 Dec 19;9:3167.  

 Chemical & Physical Properties

Molecular Formula C15H12D6N6O6S
Molecular Weight 416.44200
Exact Mass 416.13900
PSA 164.58000
LogP 1.58630

 Synonyms

2-[[4,6-bis(trideuteriomethoxy)pyrimidin-2-yl]carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide