α-Galactosidase (EC 3.2.1.22), that is, α-galactosidase, is a glycoside hydrolase that widely exists in animals, plants and microorganisms, and is often used in biochemical research. α-Galactosidase catalyzes the hydrolysis of α-1,6-linked terminal galactose residues, including galactooligosaccharides, galactomannans, and galactolipids. Catalyzes many catabolic processes including cleavage of glycoproteins, glycolipids and polysaccharides[1].
Tryptamine is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter.
Chlorophosphonazo III is a sensitive reagent for both calcium and magnesium. It is possible to determine calcium alone at pH 2.2 and calcium and magnesium at pH 7.0. Chlorophosphonazo III can also be used for the spectrophotometric determination of titanium, zirconium, thorium, and scandium, quinquevalent actinide elements, and protactinium[1].
Methyl 4-(2-hydroxyethyl)benzoate-13C6,d2 is 13C and deuterated labeled Methyl 4-(2-hydroxyethyl)benzoate (HY-W092298).
Calycosin-7-O-β-D-glucoside, a melanin biosynthesis inhibitor, is isolated from the methanol extract of astragalus. IC50 value: 68 μM in inhibition of Tyrosinase Target:In vitro: Calycosin-7-O-β-d-glucoside showed a melanin biosynthesis inhibition zone in a culture plate of Streptomyces bikiniensis. Furthermore, 75.78 μM of calycosin-7-O-β-d-glucoside dramatically decreased 50% of the melanin content on Melan-a cells without any apparent cytotoxicity [1]. Calycosin-7-O-β-D-glucoside was revealed to scavenge NO, inhibit the activities of MMP-2 and MMP-9, and attenuate cell death in the in vitro cultured brain microvascular endothelial cells under OGD condition.In vivo: Calycosin-7-O-β-D-glucoside treatment significantly reduced infarct volume, histological damage and blood–brain barrier permeability in the in vivo MCAO ischemia–reperfusion rat model [2]. To reveal its physiological functions under stress, seedlings with different isoflavonoid levels were established using a phenylalanine ammonia lyase (PAL) enzyme inhibitor, l-α-aminooxy-β-phenylpropionic acid (AOPP). The results showed that the significant promotion of antioxidant capacity in this species might be associated with the remarkable accumulation of Calycosin-7-O-β-D-glucoside after cold pretreatment. The results provided the first evidence that a type of isoflavonoid, Calycosin-7-O-β-D-glucoside, might play a very important role against freezing stress in vivo [3].
LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for 3H-LTC4 sites.
Fmoc-β-HoGlu(OtBu)-OH is a glutamic acid derivative[1].
6-TAMRA maleimide is a fluorescent dye composed of the fluorescent group of an avidin derivative and a maleimide group.
Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a 4-O-sulfamoyl-4-biphenyl based compound and can be used for synthesis of other compounds[1].
(Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl) is a biologically active peptide.
D-Praziquanamine is the inactive isomer of L-Praziquanamine (HY-N1765), and can be used as an experimental control. L-Praziquanamine is a natural product.
Congo red is an azo dye. Congo red (CR) binding been used as a diagnostic test for the presence of amyloid in tissue sections.
Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of drug and etc[1].
Cixiophiopogon A, a steroidal glycoside, obtained from the tuberous roots of Ophiopogon japonicus (Liliaceae)[1].
Guvacine ethyl ester (3.1b) is an alkaloid that can be found in betel nut. Guvacine ethyl ester can be used in the synthesis of GABA uptake inhibitor[1][2].
8-(2,4,6-Trimethylphenyl)-BODIPY is a highly fluorescent dye, can be used as photosensitizer or synthesize other BODIPY-based photosensitizer (λabs=502 nm, λemmax=516 nm)[1].(*abs: main absorption maxima)
(E)-Ethyl cinnamate can be isolated from davana oil[1].
Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide.
Boscialin ((-)-Boscialin) can be isolated from the leaves of the African medicinal plant Boscia salicifolia[1].
5-Fluoro-2′-deoxy-UTP can be used as a substrate for DNA synthesis[1].
Abz-Val-Asn-Leu-Asp-Ala-Glu-EDDnp is a quenched fluorometric substrate[1].
Calcium hydrogen phosphate dihydrate, also known as CHPD or DCPD.Calcium hydrogen phosphate dihydrate can be found quite frequently in urinary calculi stones. Calcium hydrogen phosphate dihydrate can be used as an excipient, such as diluent, adsorbent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
WAY-655978 is an active molecule.
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside, obtained from D-ribose, is also an intermediate for the synthesis of riboside-containing arsenic compound[1].
3-Feruloyl-4-caffeoylquinic acidis acaffeoyl, feruloyl quinic acidderivativeisolated fromroasted C.arabica[1].
Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT)[1].
Foroxymithine is an inhibitor of angiotensin converting enzyme.
N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity[1].
Pyridoxal-d3 is the deuterium labeled Pyridoxal[1].
Luteolin 7-diglucuronide is the major flavonoid isolated from Aloysia triphylla and Verbena officinalis[1].