Name | poly(2-hydroxyethyl methacrylate) macromolecule |
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Synonyms |
2-Hydroxyethyl methacrylate
MFCD00084374 |
Description | Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of drug and etc[1]. |
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Related Catalog | |
In Vitro | Poly(2-hydroxyethyl methacrylate) (PolyHEMA) retains moisture content similar to the live tissue and is resistant to degradation and absorption by the host cells. It can be easily manufactured in a variety of shapes and can be readily sterilized[1]. Proliferation rate of the cells that had been cultured on Poly(2-hydroxyethyl methacrylate) is reduced; Poly(2-hydroxyethyl methacrylate) does not induce cell death in the hRPE cultures. Human retinal pigment epithelium (RPE) cells cultured on Poly(2-hydroxyethyl methacrylate) formed many giant spheroid colonies. The giant colonies are re-cultured and the presence of retinal progenitor markers and markers of hRPE cells are detected in cell cultures on Poly(2-hydroxyethyl methacrylate)[1]. |
References |
Density | 1.054g/cm3 |
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Boiling Point | 189ºC at 760mmHg |
Molecular Formula | C6H10O3 |
Molecular Weight | 130.14200 |
Flash Point | 97.2ºC |
Exact Mass | 130.06300 |
PSA | 46.53000 |
LogP | 0.09800 |
Appearance | powder |
Vapour Pressure | 0.159mmHg at 25°C |
Index of Refraction | 1.442 |
Water Solubility | ethanol: 120 mg/mL |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Safety Phrases | 24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |