tryptamine

Modify Date: 2024-01-02 18:37:53

tryptamine Structure
tryptamine structure
Common Name tryptamine
CAS Number 61-54-1 Molecular Weight 160.216
Density 1.2±0.1 g/cm3 Boiling Point 378.8±0.0 °C at 760 mmHg
Molecular Formula C10H12N2 Melting Point 113-116 °C(lit.)
MSDS Chinese USA Flash Point 187.7±8.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of tryptamine


Tryptamine is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter.

 Names

Name tryptamine
Synonym More Synonyms

 tryptamine Biological Activity

Description Tryptamine is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Jones RS, et al. Tryptamine: a neuromodulator or neurotransmitter in mammalian brain? Prog Neurobiol. 1982;19(1-2):117-39.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 378.8±0.0 °C at 760 mmHg
Melting Point 113-116 °C(lit.)
Molecular Formula C10H12N2
Molecular Weight 160.216
Flash Point 187.7±8.1 °C
Exact Mass 160.100052
PSA 41.81000
LogP 1.38
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.669
Water Solubility negligible

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL4020000
CHEMICAL NAME :
Indole, 3-(2-aminoethyl)-
CAS REGISTRY NUMBER :
61-54-1
BEILSTEIN REFERENCE NO. :
0125513
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H12-N2
MOLECULAR WEIGHT :
160.24
WISWESSER LINE NOTATION :
T56 BMJ D2Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
223 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 66,1692,1977
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,453,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 22,313,1970

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 20/21/22-36/37/38-41-37/38-22
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NL4020000
HS Code 29339990

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

2-(1H-Indol-3-yl)ethylamine
Tryptamine
1H-Indole-3-ethanamine
2-indol-3-yl-ethylamine
Indole-ethylamine
L-TRYPTAMINE
EINECS 200-510-5
2-Indol-3-yl-aethylamin
Tryptamin
3-Indoleethanamine
2-(1H-Indol-3-yl)ethanamine
MFCD00005661
TRYPTAMINE(P)
T56 BMJ D2Z
[2-(1H-indol-3-yl)-ethyl]amine
TRIPTAMINE
(1H-indol-3-yl)ethanamine
2-indol-3-ylethylamine
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