tryptamine
Names
[ CAS No. ]:
61-54-1
[ Name ]:
tryptamine
[Synonym ]:
2-(1H-Indol-3-yl)ethylamine
Tryptamine
1H-Indole-3-ethanamine
2-indol-3-yl-ethylamine
Indole-ethylamine
L-TRYPTAMINE
EINECS 200-510-5
2-Indol-3-yl-aethylamin
Tryptamin
3-Indoleethanamine
2-(1H-Indol-3-yl)ethanamine
MFCD00005661
TRYPTAMINE(P)
T56 BMJ D2Z
[2-(1H-indol-3-yl)-ethyl]amine
TRIPTAMINE
(1H-indol-3-yl)ethanamine
2-indol-3-ylethylamine
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
378.8±0.0 °C at 760 mmHg
[ Melting Point ]:
113-116 °C(lit.)
[ Molecular Formula ]:
C10H12N2
[ Molecular Weight ]:
160.216
[ Flash Point ]:
187.7±8.1 °C
[ Exact Mass ]:
160.100052
[ PSA ]:
41.81000
[ LogP ]:
1.38
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.669
[ Water Solubility ]:
negligible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL4020000
- CHEMICAL NAME :
- Indole, 3-(2-aminoethyl)-
- CAS REGISTRY NUMBER :
- 61-54-1
- BEILSTEIN REFERENCE NO. :
- 0125513
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H12-N2
- MOLECULAR WEIGHT :
- 160.24
- WISWESSER LINE NOTATION :
- T56 BMJ D2Z
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 223 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 66,1692,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,453,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 22,313,1970
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
20/21/22-36/37/38-41-37/38-22
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NL4020000
[ HS Code ]:
29339990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Agric. Food Chem. 63 , 5670-81, (2015)
In sparkling wines, mannoproteins released during yeast autolysis largely affect their final quality. This process is very slow and may take several months. The aim of this work was to study the effec...
Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline.Chem. Commun. (Camb.) 49(19) , 1954-6, (2013)
Starting from (S)-tryptophanol, a formal synthesis of ent-rhynchophylline and ent-isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and alkylation reactions, and the f...
A separation of tyramine on a 2-(4-methoxyphenyl)ethylamine imprinted polymer: an answer from theoretical and experimental studies.Talanta 129 , 155-64, (2014)
A 2-(4-methoxyphenyl)ethylamine imprinted polymer (MIP) was successfully applied for the selective separation of tyramine. A computational analysis was used to predict the affinity of the polymer matr...