Ethyl 4'-hydroxy-4-biphenylcarboxylate

Modify Date: 2025-08-26 10:14:33

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure
Ethyl 4'-hydroxy-4-biphenylcarboxylate structure
Common Name Ethyl 4'-hydroxy-4-biphenylcarboxylate
CAS Number 50670-76-3 Molecular Weight 242.270
Density 1.2±0.1 g/cm3 Boiling Point 392.0±25.0 °C at 760 mmHg
Molecular Formula C15H14O3 Melting Point 142-144ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 165.7±15.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Ethyl 4'-hydroxy-4-biphenylcarboxylate


Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a 4-O-sulfamoyl-4-biphenyl based compound and can be used for synthesis of other compounds[1].

 Names

Name ethyl 4-(4-hydroxyphenyl)benzoate
Synonym More Synonyms

 Ethyl 4'-hydroxy-4-biphenylcarboxylate Biological Activity

Description Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a 4-O-sulfamoyl-4-biphenyl based compound and can be used for synthesis of other compounds[1].
Related Catalog
References

[1]. Ahmed S, et al. Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES). J Steroid Biochem Mol Biol. 2002 Nov;82(4-5):425-35.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 392.0±25.0 °C at 760 mmHg
Melting Point 142-144ºC (dec.)(lit.)
Molecular Formula C15H14O3
Molecular Weight 242.270
Flash Point 165.7±15.9 °C
Exact Mass 242.094299
PSA 46.53000
LogP 3.60
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.581
InChIKey FYXQIMAAEMCZLV-UHFFFAOYSA-N
SMILES CCOC(=O)c1ccc(-c2ccc(O)cc2)cc1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
HS Code 2922299090

 Synthetic Route

~92%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Busson; Oertegren; Ihre; Gedde; Hult; Andersson; Eriksson; Lindgren Macromolecules, 2002 , vol. 35, # 5 p. 1663 - 1671

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: He, Lingyan; Zhang, Liang; Liu, Xiaofeng; Li, Xianghua; Zheng, Mingyue; Li, HongLin; Yu, Kunqian; Chen, Kaixian; Shen, Xu; Jiang, Hualiang; Liu, Hong Journal of Medicinal Chemistry, 2009 , vol. 52, # 8 p. 2465 - 2481

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Surendranath, V.; Fishel, D. L.; Vries, A de; Mahmood, R.; Johnson, D. L. Molecular Crystals and Liquid Crystals (1969-1991), 1985 , vol. 131, p. 1 - 8

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Abdu-Allah, Hajjaj H. M.; Tamanaka, Taichi; Yu, Jie; Zhuoyuan, Lu; Sadagopan, Magesh; Adachi, Takahiro; Tsubata, Takeshi; Kelm, Soerge; Ishida, Hideharu; Kiso, Makoto Journal of Medicinal Chemistry, 2008 , vol. 51, # 21 p. 6665 - 6681

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Surendranath, V.; Fishel, D. L.; Vries, A de; Mahmood, R.; Johnson, D. L. Molecular Crystals and Liquid Crystals (1969-1991), 1985 , vol. 131, p. 1 - 8

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Surendranath, V.; Fishel, D. L.; Vries, A de; Mahmood, R.; Johnson, D. L. Molecular Crystals and Liquid Crystals (1969-1991), 1985 , vol. 131, p. 1 - 8

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Surendranath, V.; Fishel, D. L.; Vries, A de; Mahmood, R.; Johnson, D. L. Molecular Crystals and Liquid Crystals (1969-1991), 1985 , vol. 131, p. 1 - 8

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Surendranath, V.; Fishel, D. L.; Vries, A de; Mahmood, R.; Johnson, D. L. Molecular Crystals and Liquid Crystals (1969-1991), 1985 , vol. 131, p. 1 - 8

~%

Ethyl 4'-hydroxy-4-biphenylcarboxylate Structure

Ethyl 4'-hydrox...

CAS#:50670-76-3

Literature: Lee, Myongsoo; Oh, Nam-Keun Journal of Materials Chemistry, 1996 , vol. 6, # 7 p. 1079 - 1086

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

4'-hydroxybiphenyl-4-carboxylic acid ethyl ester
Ethyl 4'-hydroxybiphenyl-4-carboxylate
ethylhydroxybiphenylcarboxylate
ethyl 4'-hydroxy-4-biphneyl carboxylate
[1,1'-Biphenyl]-4-carboxylic acid, 4'-hydroxy-, ethyl ester
Ethyl 4'-hydroxy-4-biphenylcarboxylate
ethyl 4'-hydroxy[1,1'-biphenyl]-4-carboxylate
4'-hydroxy-[1,1'-biphenyl]-4-carboxylic acid,ethyl ester
4'-Hydroxy-biphenyl-4-carboxylic acid ethyl ester
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